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US 2014/0227275 A1Published application
Methods of treating and diagnosing pancreatitis
AssigneeIncyte Corporation
InventorsRoger T. COLEMAN, Olga Bandman, Craig G. Wilde
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AssigneeIncyte Corporation
InventorsRoger T. COLEMAN, Olga Bandman, Craig G. Wilde
Estimating the term…
The present invention provides nucleotide and amino acid sequences that identify and encode novel expressed chemokines (PANEC-1 and PANEC-2) from human pancreas cells. The present invention also provides for antisense molecules to the nucleotide sequences which encode PANEC-1 and PANEC-2, expression vectors for the production of purified PANEC-1 and PANEC-2, antibodies capable of binding specifically to PANEC-1 and PANEC-2, hybridization probes or oligonucleotides for the detection of PANEC-1- or PANEC-2-encoding nucleotide sequences, genetically engineered host cells for the expression of PANEC-1 and PANEC-2, diagnostic tests for chemokine activation based on PANEC-1- and PANEC-2-encoding nucleic acid molecules and antibodies capable of binding specifically to the protein.
(canceled)
A method of treating an activated or inflamed condition of the pancreas comprising administering to a subject in need an effective dosage of a pharmaceutical composition comprising:
A diagnostic test for pancreatic inflammation in a subject comprising the steps of:
A diagnostic test for pancreatic inflammation in a subject comprising the steps of:
Dependencies are inferred from the claim text.