US 2014/0227269 A1Published application

Therapeutic nuclease compositions and methods

AssigneeUniversity of Washington

InventorsJeffrey A. Ledbetter, Martha Hayden-Ledbetter, Keith Elkon, Xizhang Sun

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Abstract

Hybrid nuclease molecules and methods for treating an immune-related disease or disorder in a mammal, and a pharmaceutical composition for treating an immune-related disease in a mammal.

Claims12

Dependent claims

A hybrid nuclease molecule comprising a first nuclease domain and an Fc domain, wherein the first nuclease domain is operatively coupled to the Fc domain.

Dependencies are inferred from the claim text.

Facts

Application: 14/258,319Filed 22 Apr 2014
Priority: 2 Nov 2009
Published: 14 Aug 2014
Term ends: Not estimatedThe source records don’t support an estimate.

Classification37 codes

C12N 9/22
Acting on ester bonds: ribonucleases [RNase]; Deoxyribonucleases [DNase]
A61P 1/00
Drugs for disorders of the alimentary tract or the digestive system
A61P 1/04
Drugs for disorders of the alimentary tract or the digestive system: for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of…
A61P 1/16
Drugs for disorders of the alimentary tract or the digestive system: for liver or gallbladder disorders, e.g. hepatoprotective agents,…

Family

Application61/257,458Us provisional application · filed 2 Nov 2009
Application61/370,752Us provisional application · filed 4 Aug 2010
Application13/505,421Continuation · filed 16 Jul 2012
Application14/258,319Continuation
US 2013/0089546 A1Published application
US 2014/0227269 A1This patent

From the US filing history. Foreign family members aren’t listed.

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