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US 2014/0227238 A1Published application
Peptides having protective effect towards the inflammatory activity of peptide 31-43 of a-gliadin in celiac disease
AssigneesIstituto Superiore di Sanita, CRA-Sonsiglio per La Ricerca E LA
InventorsMarco Silano, Luigi Cattivelli, Pasquale De Vita, Luigi Maiuri, Donatella Bianca Maria Ficco
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Abstract
The present invention concerns peptides having protective effect towards inflammatory activity of a-gliadin 31-43 peptide in celiac disease and therefore can be used for preventive and therapeutic purpose by administration thereof to subjects at high risk to develop celiac disease and/or celiac subjects just before a gluten containing meal to be ingested.
Claims20
A peptide comprising sequence:
- (SEQ ID No:
- 4)
- QQPQ[X]nQPF
- wherein X is any amino acid;
- n is an integer equal or greater than 1, X amino acids being the same or different each other when n is higher than 1, provided that [X]n is different than DAV.
2 more elements
A method of preparing food for celiac subjects, the method comprising
- mixing the food with a plant variety naturally expressing peptide SEQ ID NO:
- 2.
Dependencies are inferred from the claim text.