Ophthalmic and Otorhinolaryngological Device Materials

A polymeric ophthalmic or otorhinolaryngological device material comprising

• a) 70 to 98% (w/w) of a monofunctional acrylate or methacrylate monomer of formula [1]:
• wherein
• B=—O(CH2)n—, —(OCH2CH2)n—, —NH(CH2)n—, or —NCH3(CH2)n—;
• R1=H, CH3, CH2CH3, or CH2OH;
• n=0-12;
• A=C6H5 or O(CH2)mC6H5, where the C6H5 group is optionally substituted with —(CH2)nH, —O(CH2)nH, —CH(CH3)2, —C6H5, —OC6H5, —CH2C6H5, F, Cl, Br, or I;
• and
• m=0-18;
• b) a difunctional acrylate or methacrylate cross-linking monomer of formula [2]:
• wherein
• R2, R3 independently=H, CH3, CH2CH3, or CH2OH;
• W, W′ independently=O(CH2)d, NH(CH2)d, NCH3(CH2)d, O(CH2)dC6H4, O(CH2CH2O)dCH2, O(CH2CH2CH2O)dCH2, O(CH2CH2CH2CH2O)dCH2, or nothing;
• J=(CH2)a, O(CH2CH2O)b, O, or nothing, provided that if W and W′=nothing, then J≠nothing;
• d=0-12;
• a=1-12;
• b=1-24;
• and c) 2 to 4% (w/w) of a hydrophillic side-chain macromer of formula:
• wherein for formulas:
• e=1-50;
• X=—O—, NH—, —N(CH3)—, —N(CH2CH3)—, or —N(C6H5)—;
• Y=H, —(CH2)pOH, —CH2CH2N(CH3)2, —CH2CH2N(CH2CH3)2, —CH2CH(OH)CH2OH, —(CH2CH2O)qCH3, —(CH2CH2O)qH, —(CH2CH2O)qC6H5, or
• p=1-12;
• q=1-230;
• T, T′ independently=O(CH2)d′, NH(CH2)d′, NCH3(CH2)d′, O(CH2)d′C6H4, O(CH2CH2O)d′CH2, O(CH2CH2CH2O)d′CH2, O(CH2CH2CH2CH2O)d′CH2, or nothing;
• K=(CH2)a′, O(CH2CH2O)b′, O, or nothing, provided that if T and T′=nothing, then K≠nothing;
• d′=0-12;
• a′=1-12;
• b′=1-24;
• L=H, Cl, Br, —CH2C(O)CH3, CH2C(O)C(CH3)3, —CH2C(O)C6H5, —CH2C(O)C6H4OH, —CH2C(O)C6H4OCH3,
• d′=0-12;
• a′=1-12;
• b′=1-24;
• L=H, Cl, Br, —CH2C(O)CH3, CH2C(O)C(CH3)3, —CH2C(O)C6H5, —CH2C(O)C6H4OH, —CH2C(O)C6H4OCH3,
• or
• —CH2CH═CH2;
• R4, R5 independently=H, CH3, CH2CH3, CH2CH2CH3, CH(CH3)2, CH2CH2CH2CH3, or CH2CH(CH3)2;
• R7, R8 independently=H, CH3, CH2CH3, or CH2OH;
• M=—(CH2)a″—;
• and
• a″=2-20.