Absorbable Multi-Putty Bone Cements and Hemostatic Compositions and Methods of Use
AssigneeAbyrx, Inc.
InventorsRao Bezwada, Aniq Darr, Richard L. Kronenthal, John Pacifico
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Abstract
The present invention relates to absorbable polyurethane compositions suitable for use in bone repair or reconstruction. The present invention relates to the field of polyurethane-based cements, and putties for use in bone hemostasis, repair and reconstruction. The putty compositions may comprise a mixture of two or more individual putties formed through mixing of one or more reactive components and one or more additive (filler) components. Also disclosed herein are methods of using the putty compositions in medical applications to repair gaps or fractures, or to aid in tissue growth or adhesion.
Claims19
1-35. (canceled)
A curable, absorbable polymeric composition formed by the reaction of two individual compositions, putty A and putty B, wherein putty A comprises an isocyanate component and one or more additive components and putty B comprises an absorbable polyol, a chain extender, and one or more additive components.
A binary package or article of manufacture comprising separated first and second components, wherein the first component comprises a curable prepolymer of a polyaromatic polyisocyanate having a hydrolysable linkage bridging at least two of the aromatic rings and a polyaromatic polyisocyanate in the form of a putty;
- and the second component, also in the form of a putty, comprises an absorbable polyol, a chain extender and none, or one or more additives.
Dependencies are inferred from the claim text.