Back to results
US 2014/0213658 A1Published application
Topical compositions and methods for making and using same
AssigneeMerz Pharmaceuticals, LLC
InventorsBhushan Hardas, Donna Dalton
Life of this patent
Estimating the term…
Abstract
The present invention relates to improved topical gel compositions comprising an active agent, and uses thereof.
Claims19
A gel composition for topical administration consisting essentially of:
- (i) naftifine or a pharmaceutically acceptable salt thereof, present in an amount of from about 0.5 wt % to about 4 wt %;
- (ii) a first solvent which is a glycol solvent, present in an amount of from about 10 wt % to about 25 wt %;
- (iii) a second solvent which is an alkyl alcohol solvent, present in an amount of from about 10 wt % to about 25 wt %;
- (iv) a non-carbomer rheology modifier selected from a hydroxy cellulose, present in an amount of from about 0.75 wt % to about 2.25 wt %;
- (v) a polysorbate solubilizing agent present in an amount of from about 3 wt % to about 8 wt %;
- (vi) a pH adjuster selected from an amine base;
- and
- optionally one or more of:
- water, a preservative, a chelating agent, a coloring agent, and a fragrance,
- wherein the gel composition has a pH of about 4.5 to about 6.0.
7 more elements
7-8. (canceled)
(canceled)
Dependencies are inferred from the claim text.