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US 2014/0213618 A1Published application
Synthesis of epothilones, intermediates thereto and analogues thereof
AssigneeSloan-Kettering Institute for Cancer Research
InventorsSamuel J. Danishefsky, Alexey Rivkin, Yoshimura Fumihiko, Ting-Chao Chou, Ana E. Gabarda, Huajin Dong
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Abstract
The present invention provides compounds of formula (I): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (I) and provides methods of treating cancer comprising administering a compound of formula (I).
Claims12
1-117. (canceled)
A compound having the formula:
- wherein:
- R2 is a substituted or unsubstituted aryl, heteroaryl, arylalkyl, or heteroarylalkyl moiety;
- R5 and R6 are each independently hydrogen or a protecting group;
- and
- RB is —CF3.
2 more elements
Dependencies are inferred from the claim text.