Pharmaceutical Formulation Containing Gelling Agent
AssigneesPurdue Pharma L.P., Purdue Pharmaceuticals L.P., The P.F. Laboratories, Inc.
InventorsCurtis Wright, Benjamin Oshlack, Christopher Breder
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Abstract
Disclosed in certain embodiments is a controlled release oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse together with one or more pharmaceutically acceptable excipients; the dosage form further including a gelling agent in an effective amount to impart a viscosity unsuitable for administration selected from the group consisting of parenteral and nasal administration to a solubilized mixture formed when the dosage form is crushed and mixed with from about 0.5 to about 10 ml of an aqueous liquid; the dosage form providing a therapeutic effect for at least about 12 hours when orally administered to a human patient.
Claims13
1-40. (canceled)
A therapeutic pharmaceutical composition comprising:
- a mixture including (a) a water soluble drug susceptible to abuse;
- (b) a gel-forming polymer;
- (c) a disintegrant;
- and (d) a surfactant;
- wherein the pharmaceutical composition exhibits an immediate release profile.
Dependencies are inferred from the claim text.