Compositions and treatments for dystrophies
AssigneeMd Pharma AB
InventorsMadeleine Durbeej-Hjalt, Virginie Carmingnac
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Abstract
The present invention provides an inhibitor of intracellular protein degradation for use in the treatment and prevention of muscular dystrophy in a mammal. In particular, the invention provides an autophagy inhibitor and/or an inhibitor of the ubiquitin-proteasome system (such as a proteasome inhibitor) for use in the treatment and prevention of muscular dystrophy (such as congenital muscular dystrophy [e.g. MDC1A) and Duchenne muscular dystrophy [DMD]). The invention further provides corresponding methods of treatment and prevention of muscular dystrophy.
Claims21
1-54. (canceled)
A method for treating or preventing muscular dystrophy in a mammal comprising administering an effective amount of an autophagy inhibitor to the mammal.
Dependencies are inferred from the claim text.