Thymosin alpha peptide for preventing, reducing the severity of, and treating infection
OwnerCynthia W. Tuthillinventor
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OwnerCynthia W. Tuthillinventor
Estimating the term…
The present invention provides methods for preventing, treating, or reducing the severity of infection, including bacterial, viral, and fungal infections, and including infections of more complex etiology. The invention involves the administration of an alpha thymosin peptide regimen, so as to prime or enhance a patient's immune response for pathogen exposure. In certain embodiments, the alpha thymosin regimen is scheduled or timed with respect to potential or expected pathogen exposures. The regimen of alpha thymosin peptide as described herein provides the patient with a more robust immune response to pathogen exposure, including higher antibody titers and/or a more rapid antibody response. In certain embodiments, the patient is immunodeficient or immunecompromised, and/or the patient is hospitalized or scheduled for hospitalization, such that the regimen of alpha thymosin peptide helps to protect the patient from, or reduce the severity of nosocomial infection or illness.
A method for protecting a patient from infection, or reducing the severity of an infection, comprising, initiating an efficient regimen of alpha thymosin peptide prior to an event predicted to result in microbial exposure or opportunism, so as to prevent an infection or reduce the severity of a resulting infection.
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A method for treating an infection, comprising, administering an efficient regimen of alpha thymosin peptide so as to treat or reduce the severity of the infection.
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A method for reducing the rate or incidence of hospital-acquired infection, comprising initiating an alpha thymosin regimen for at-risk patients upon admittance to the hospital, the regimen comprising administration of alpha thymosin peptide at a frequency of once per every 5 to 10 days of hospitalization.
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A method for treating a hospital-acquired infection or infection suspected of being drug resistant, comprising, administering alpha thymosin peptide at a dose of from 2 to 8 mg either once or two times daily, or every other day, for from 3 to 14 days.
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Dependencies are inferred from the claim text.