US 2014/0212968 A1Published application

Synthetic matrices for long term expansion of pluripotent human embryonic stem cells

AssigneeThe Regents of the University of California

InventorsShyni VARGHESE, Chien-Wen CHANG, Yongsung HWANG

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Abstract

Provided herein is a synthetic polymer-based hydrogel for the self-renewal and expansion of human stem cells such as embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). Also provided are methods of making and using the same.

Claims8

Dependent claims

A method for expanding stem cells comprising seeding a stem cell onto a synthetic hydrogel, wherein the synthetic hydrogel comprises a heparin mimetic moiety and an acrylamide monomer.

Dependencies are inferred from the claim text.

Facts

Application: 14/256,753Filed 18 Apr 2014
Priority: 6 Dec 2011
Published: 31 Jul 2014
Term ends: Not estimatedThe source records don’t support an estimate.

Classification11 codes

C12N 5/0606
Embryonic cells ; Embryoid bodies: pluripotent embryonic cells, e.g. embryonic stem cells [ES]
C08F 12/30
Substituted by hetero atoms or groups containing heteroatoms: sulfur
C08F 220/56
Amides , e.g. N,N-dimethylacrylamide or N-isopropylacrylamide: acrylamide; Methacrylamide
C08F 222/38
Amides or imides: amides

Family

Application61/567,588Us provisional application · filed 6 Dec 2011
Application13/706,900Division · filed 6 Dec 2012
Application14/256,753Division
US 2013/0177980 A1Published application
US 2014/0212968 A1This patent

From the US filing history. Foreign family members aren’t listed.

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