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US 2014/0212945 A1Published application
Rna targeting compounds and methods for making and using same
AssigneeThe Research Foundation for The State University of New York
InventorMatthew David Disney
Life of this patent
Estimating the term…
Abstract
Disclosed are RNA targeting compounds, methods for using the subject RNA targeting compounds to treat myotonic dystrophy and other diseases are also disclosed.
Claims8
A compound having the formula:
- wherein j is an integer from 1 to 100;
- each i is the same or different and is zero or an integer from 1 to 100;
- each Z1 represents the same or different linking moiety;
- each R1 is the same or different and represents an alkyl group or an aryl group;
- each Q1 is the same or different and is selected from aminoglycoside sugars and bis-benzimidazoles;
- Q2 is an unsubstituted or substituted alkyl group;
- and Q3 has the formula —NR2R3, R2 has the formula —Z1-Q1, and R3 is a hydrogen atom.
4 more elements
A compound having the formula:
- wherein j is an integer from 1 to 100;
- each i is the same or different and is zero or an integer from 1 to 100;
- each Z1 represents the same or different linking moiety and has one of the following formulae:
- wherein y is an integer from 1 to 6, and wherein z is an integer from 1 to 6;
- each R1 is the same or different and represents an alkyl group or an aryl group;
- each Q1 represents the same or different ligand and is selected from protein, polypeptides, carbohydrates, non-nucleic acid biopolymers, peptoids, whole cells, aminoglycoside sugars, and bis-benzimidazoles;
- Q2 is an unsubstituted or substituted alkyl group;
- and Q3 is a halogen, an alkyl group, an aryl group, or an amine.
5 more elements
A compound having the formula:
- wherein j is an integer from 1 to 100;
- each i is the same or different and is zero or an integer from 1 to 100;
- each Z1 represents the same or different linking moiety;
- each R1 is the same or different and represents an alkyl group or an aryl group;
- each Q1 represents the same or different ligand and is selected from protein, polypeptides, carbohydrates, non-nucleic acid biopolymers, peptoids, whole cells, aminoglycoside sugars, and bis-benzimidazoles;
- Q2 is an unsubstituted or substituted alkyl group;
- and Q3 is a halogen, an alkyl group, an aryl group, or an amine.
4 more elements
Dependencies are inferred from the claim text.