Back to results
US 2014/0212504 A1Published application
Phospholipid-based powders for drug delivery
AssigneeNovartis AG
InventorsJeffry G. WEERS, Thomas E. TARARA, Luis A. DELLAMARY, Jean G. RIESS, Ernest G. SCHUTT
Life of this patent
Estimating the term…
Abstract
Phospholipid based powders for drug delivery applications are disclosed. The powders comprise a polyvalent cation in an amount effective to increase the gel-to-liquid crystal transition temperature of the particle compared to particles without the polyvalent cation. The powders are hollow and porous and are preferably administered via inhalation.
Claims19
A particulate composition for delivery to the pulmonary system, the particulate composition comprising:
- dry particles, wherein each particle comprises an active agent, a phospholipid, and a polyvalent cation, wherein the particles have a mass median diameter of 0.5 to 5 microns, and wherein the particulate composition is characterized by being deliverable at an emitted dose of at least 54.55%.
Dependencies are inferred from the claim text.