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US 2014/0212491 A1Published application
Combination formulation of two antiviral compounds
OwnerBen Chal, Erik Mogalian +4inventors
InventorsBen Chal, Erik Mogalian, Reza Oliyai, Rowchanak Pakdaman, Dimitrios Stefanidis, Vahid Zia
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Abstract
Disclosed are pharmaceutical compositions having an effective amount of substantially amorphous ledipasvir and an effective amount of substantially crystalline sofosbuvir.
Claims33
A pharmaceutical composition comprising:
- a) an effective amount of ledipasvir having the formula:
- wherein ledipasvir is substantially amorphous;
- and
- b) an effective amount of sofosbuvir having the formula:
- wherein sofosbuvir is substantially crystalline.
2 more elements
3-5. (canceled)
7-10. (canceled)
12-67. (canceled)
Dependencies are inferred from the claim text.