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US 2014/0212487 A1Published application
Solid dispersion formulation of an antiviral compound
OwnerErik Mogalian, Reza Oliyai +2inventors
InventorsErik Mogalian, Reza Oliyai, Dimitrios Stefanidis, Vahid Zia
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Abstract
Disclosed are solid dispersions comprising ledipasvir, wherein ledipasvir is dispersed within a polymer matrix formed by a pharmaceutically acceptable polymer, and further wherein ledipasvir is substantially amorphous. Also disclosed are pharmaceutical compositions comprising solid dispersion and methods of using the solid dispersion.
Claims42
A solid dispersion comprising ledipasvir having the formula:
- wherein ledipasvir is dispersed within a polymer matrix formed by a pharmaceutically acceptable polymer, and further wherein ledipasvir is substantially amorphous.
Dependencies are inferred from the claim text.