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US 2014/0212475 A1Published application
Anti-cancer compositions and methods
AssigneeThe Penn State Research Foundation
InventorsGavin P. Robertson, Chandagalu D. Raghavendra Gowda, Dhimant H. Desai, Shantu G. Amin
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Abstract
Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject having or suspected of having cancer are provided according to aspects of the present invention which include administering a therapeutically effective amount of a pharmaceutical composition including a selenium-containing COX-2 inhibitor.
Claims27
A composition comprising
- a selenium-containing COX-2 inhibitor, selected from the group consisting of:
- selenocoxib-1-glutathione (selenocoxib-1-GSH), selenocoxib-1-cysteine, selenocoxib-1-N-aceylcysteine (selenocoxib-1-NAC) and a mixture of two or more thereof.
A pharmaceutical composition, comprising:
- a selenium-containing COX-2 inhibitor selected from the group consisting of selenocoxib-1-GSH, selenocoxib-1-cysteine, selenocoxib-1-NAC;
- and a mixture of two or more thereof;
- and
- a pharmaceutically acceptable carrier.
1 more element
A method of treating a subject, comprising:
- administering a therapeutically effective amount of a pharmaceutical composition comprising a selenium-containing COX-2 inhibitor selected from the group consisting of:
- selenocoxib-1-GSH, selenocoxib-1-cysteine, selenocoxib-1-NAC and a mixture of two or more thereof.
Dependencies are inferred from the claim text.