Protein-based streptococcus pneumoniae vaccines
AssigneeBen-Gurion University of the Negev Research and Development Authority
InventorYaffa MIZRACHI NEBENZAHL
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Abstract
Vaccine compositions and methods for protecting a mammalian subject against infection with S. pneumoniae are disclosed. These vaccine compositions include as the active ingredient a purified preparation of the cell wall protein ABC transporter substrate-binding protein having the Accession No. NP_344690 and the amino acid sequence set forth in SEQ ID NO: 32, optionally together with one or more pharmaceutically acceptable adjuvants.
Claims19
A vaccine composition comprising as the active ingredient a purified preparation of the cell wall protein ABC transporter substrate-binding protein having the Accession No. NP—344690 and the amino acid sequence set forth in SEQ ID NO:
- 32, optionally together with one or more pharmaceutically acceptable adjuvants.
The vaccine composition according to claim formulated for administration to an infant under four years of age.
A vaccine composition consisting essentially of, as the active ingredient, a purified preparation of the cell wall protein ABC transporter substrate-binding protein having the Accession No. NP—344690 and the amino acid sequence set forth in SEQ ID NO:
- 32, optionally together with one or more pharmaceutically acceptable adjuvants.
Dependencies are inferred from the claim text.