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US 2014/0212428 A1Published application
Human il-23 antigen binding proteins
AssigneeAmgen Inc.
InventorsJennifer E. Towne, Janet D. Cheng, Jason C. O'Neill, Yu Zhang, Yu Sun, Heather Cerne, Derek E. Piper, Randal R. Ketchem
Life of this patent
Estimating the term…
Abstract
Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided.
Claims9
1-5. (canceled)
An isolated antigen binding protein that binds IL 23, comprising:
- a CDRH1 selected from the group consisting of SEQ ID NO:
- 109;
- a CDRH2 selected from the group consisting of SEQ ID NO:
- 116;
- a CDRH3 selected from the group consisting of SEQ ID NO:
- 111;
- a CDRL1 selected from the group consisting of SEQ ID NO:
- 80;
- a CDRL2 is SEQ ID NO:
- 81;
- and
- a CDRL3 selected from the group consisting of SEQ ID NO:
- 79.
10 more elements
An isolated antigen binding protein that binds IL-23 comprising
- a heavy chain variable region comprising amino acid residues 31-37, 52-67 and 100-109 of SEQ ID NO:
- 46 or 153;
- and a light chain variable region comprising amino acid residues 24-34, 50-56 and 89-97 of SEQ ID NO:
- 15.
1 more element
8-23. (canceled)
An isolated antigen binding protein that binds IL 23, comprising
- a heavy chain variable region selected from the group consisting of SEQ ID NO:
- 46 and 153, and
- a light chain variable region selected from the group consisting of SEQ ID NO:
- 15.
1 more element
25-57. (canceled)
60-69. (canceled)
Dependencies are inferred from the claim text.