Compositions and Methods for the Treatment of Lysosomal Storage Disorders
AssigneeRegents of the University of Minnesota
InventorsBRUCE BLAZAR, JAKUB TOLAR, CATHERINE M. VERFAILLIE
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Abstract
The present invention relates to methods for providing lysosomal enzymes to a subject by administering stem cells, preferably Multipotent Adult Progenitor Cells (MAPCs). The invention further relates to methods for treating lysosomal storage disorders by administering stem cells.
Claims7
1-28. (canceled)
A method for treating a lysosomal storage disorder comprising administering stem cells to a subject having a lysosomal storage disorder, wherein the stem cells express telomerase, have undergone about 10-40 doublings in culture, and can differentiate into cell types of at least two of the endodermal, ectodermal, and mesodermal lineages.
Dependencies are inferred from the claim text.