System and Method for Joint Reconstruction of Spatial and Spectral Imaging Data
AssigneeWisconsin Alumni Research Foundation
InventorsSean B. Fain, Kevin M. Johnson, Jeremy W. Gordon
Life of this patent
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Abstract
A system and method for simultaneously generating spectral images and spatial images of a subject using a magnetic resonance imaging (MRI) system includes acquiring MR image data using a k-space sampling trajectory. The k-space sampling trajectory is designed to spatially oversample to elicit phase differences between oversampled points. The MR image data is jointly reconstructed into spatial and spectral images by resolving spatial information from spatial encoding associated with each of the oversampled points and resolving spectral information from the phase differences between the oversampled points.
Claims23
A method for simultaneously generating spectral images and spatial images of a subject using a magnetic resonance imaging (MRI) system, the steps of the method comprising:
- arranging a subject having received a dose of a hyperpolarized molecular imaging agent within a magnetic resonance imaging (MRI) system;
- acquiring MR image data from the subject according to a k-space sampling trajectory that spatially oversamples to encode both spatial frequency information and spectral frequency information in the oversampled points;
- and
- reconstructing the MR image data into spatial and spectral images using a priori knowledge of an expected chemical species associated with the molecular imaging agent and a model-based reconstruction technique.
A magnetic resonance imaging (MRI) system comprising:
- a magnet system configured to generate a magnetic field about at least a region of interest (ROI) in a subject arranged in the MRI system;
- a plurality of gradient coils configured to apply a gradient field with respect to the magnetic field;
- a radio frequency (RF) system configured to apply an excitation field to the subject and acquire MR image data from a ROI;
- a computer system programmed to:
- control the plurality of gradient coils and the RF system to acquire MR image data according to a k-space sampling trajectory designed to spatially oversample to elicit phase differences between oversampled points;
- and
- jointly reconstruct the MR image data into spatial and spectral images by resolving spatial information from spatial encoding associated with each of the oversampled points and resolving spectral information from the phase differences between the oversampled points.
A method for generating spectral images and spatial images of a subject using a magnetic resonance imaging (MRI) system, the steps of the method comprising:
- arranging a subject having received a dose of a hyperpolarized molecular imaging agent within a magnetic resonance imaging (MRI) system;
- acquiring MR image data using a k-space sampling trajectory designed to spatially oversample to elicit phase differences between oversampled points;
- and
- jointly reconstructing the MR image data into spatial and spectral images by resolving spatial information from spatial encoding associated with each of the oversampled points and resolving spectral information from the phase differences between the oversampled points.
Dependencies are inferred from the claim text.