# US 2014/0207249 A1 · Tissue Repair Implant > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2014/0207249 A1 - Document ID: US20140207249A1 - Status: Published application - Kind: A1 - Application number: 14/224,569 - Filed: 2014-03-25 - Published: 2014-07-24 - Earliest claimed: 2008-04-29 - Assignees: Proxy Biomedical Limited - Inventors: Peter Gingras; Gabriela Voskerician; Michael F. White - Web page: https://patentgrep.com/patent/US20140207249A1 ## CPC - A61L 27/3604: {characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel} - A61F 2/0063: {Implantable repair or support meshes, e.g. hernia meshes} - A61F 2/02: Prostheses implantable into the body - A61L 31/005: {Ingredients of undetermined constitution or reaction products thereof} - A61L 2430/34: for soft tissue reconstruction - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) ## Abstract Described herein are tissue repair implants comprising at least a first layer of peritoneal membrane. The first layer of peritoneal membrane can be located adjacent to a second layer of peritoneal membrane and can be in direct contact with the second layer of peritoneal membrane. Additional layers (e.g., a third or fourth layer) can be included. Where more than one layer is present, the layers can be affixed to one another. For example, a first layer of peritoneal membrane can be attached to the second layer of peritoneal membrane by an adhesive bond, suture, or staple. One or more of the peritoneal membranes can be non-crosslinked, partially crosslinked, or substantially fully crosslinked. Any of the layers of peritoneal membrane may be attached to a wall (e.g., an interior or exterior wall) of an abdominal tissue by an adhesive, suture, and/or staples. ## Claims ### Claim 1 A tissue repair implant comprising a first layer of peritoneal membrane and a second layer of peritoneal membrane. ### Claim 2 (depends on 1) The implant of claim 1, wherein the first layer of peritoneal membrane is located adjacent to the second layer of peritoneal membrane. ### Claim 3 (depends on 1) The implant of claim 1, wherein the first layer of peritoneal membrane is in direct contact with the second layer of peritoneal membrane. ### Claim 4 (depends on 1) The implant of claim 1, wherein at least one of the layers of peritoneal membrane is non-crosslinked. ### Claim 5 (depends on 1) The implant of claim 1, wherein at least one of the layers of peritoneal membrane is partially crosslinked. ### Claim 6 (depends on 1) The implant of claim 1, wherein at least one of the layers of peritoneal membrane is substantially fully crosslinked. ### Claim 7 (depends on 1) The implant of claim 1, wherein the first layer of peritoneal membrane and/or the second layer of peritoneal membrane is configured to be remodeled by in-growth of tissue. ### Claim 8 (depends on 7) The implant of claim 7, wherein the first layer of peritoneal membrane and/or the second layer of peritoneal membrane is configured to promote in-growth of tissue. ### Claim 9 (depends on 1) The implant of claim 1, wherein the first layer of peritoneal membrane and/or the second layer of peritoneal membrane is configured to promote fluid communication. ### Claim 10 (depends on 1) The implant of claim 1, wherein the first layer of peritoneal membrane and/or the second layer of peritoneal membrane is configured to be attached to an interior wall of an abdominal tissue. ### Claim 11 (depends on 1) The implant of claim 1, wherein the implant is configured to treat an abdominal hernia repair, and/or as a pelvic floor reinforcement, and/or for vaginal reconstruction, and/or as a uterine wound cover, and/or for a colorectal application, and/or for a urological application, and/or for a gynecological application. ### Claim 12 (depends on 1) The implant of claim 1, wherein the shape of the implant is pre-defined to suit the shape of an abdominal cavity. ### Claim 13 (depends on 1) The implant of claim 1, wherein the layer of peritoneal membrane comprises interrupted sutures to retain compliance. ### Claim 14 (depends on 1) The implant of claim 1, wherein the first layer of peritoneal membrane and/or the second layer of peritoneal membrane is oriented with its mesothelium surface oriented in an outward direction to generate one or more organ contacting surfaces. ### Claim 15 A graft prosthesis comprising: a purified, collagen based matrix removed from a peritoneal membrane source, the purified structure having a contaminant level making the purified structure biocompatible.