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US 2014/0199736 A1Published application
Pichia ciferrii cells and use thereof
AssigneeEvonik Degussa GmbH
InventorsTim Köhler, Christoph Schorsch, Eckhard Boles, Heiko Andrea, Mike Farwick, Steffen Schaffer
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Abstract
The invention relates to genetically modified Pichia ciferrii cells, to the use thereof and to a method of producing sphingoid bases and sphingolipids.
Claims15
An isolated Pichia ciferrii cell, characterized in that the cell has, compared to its wild type, a reduced activity of at least one of the enzymes which are encoded by the intron-free nucleic acid sequences selected from the two groups A) and B) consisting of
- A) Seq ID No 1, Seq ID No 3, Seq ID No 5, Seq ID No 7, Seq ID No 9, Seq ID No 11,
- B) a sequence which is at least 80% identical to any of the sequences Seq ID No 1, Seq ID No 3, Seq ID No 5, Seq ID No 7, Seq ID No 9, Seq ID No 11.
(canceled)
Dependencies are inferred from the claim text.