# US 2014/0195568 A1 · Object database and object database improving method

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- Number: US 2014/0195568 A1
- Document ID: US20140195568A1
- Status: Published application
- Kind: A1
- Application number: 14/233,689
- Filed: 2012-07-19
- Published: 2014-07-10
- Earliest claimed: 2011-07-19
- Assignees: Ovizio Imaging Systems NV/SA
- Inventors: Philip Mathuis; Serge Jooris; Olivier Magniette
- Web page: https://patentgrep.com/patent/US20140195568A1

## CPC

- G06F 16/289: {Object oriented databases}
- G06F 16/235: {Update request formulation}
- G16H 10/40: for data related to laboratory analysis, e.g. patient specimen analysis
- G16H 30/20: for handling medical images, e.g. DICOM, HL7 or PACS
- G16H 70/60: relating to pathologies
- G16H 50/80: for detecting, monitoring or modelling epidemics or pandemics, e.g. flu
- G06F: ELECTRIC DIGITAL DATA PROCESSING (computer systems based on specific computational models G06N)
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA

## Abstract

The current invention concerns an object database comprising a set of object entries, which comprise object properties, whereby said object properties comprise obtained object properties, which comprise DHM-obtained object properties and preferably object identification properties, characterized in that said DHM-obtained object properties comprise properties about a sample comprising said objects, said information derived from information acquired by a digital holographic microscope (DHM) and whereby preferably said object identification properties comprise information about the objects which allow identification of the object between the object database and an database. The invention furthermore discloses an object database updating method and a computing system comprising an object database and object database updating method as disclosed in the current invention.

## Claims

### Claim 1

An object database for storing information about objects in a sample, whereby said objects are analyzable by a digital holographic microscope, said database comprising a set of object entries, which comprise object properties, whereby said object properties comprise obtained object properties, which comprise digital holographic microscope (DBM)-obtained object properties and object identification properties,
characterized in that said DEM-obtained object properties comprise properties derived from information about said sample comprising said objects, said information acquired by a (DEM) and whereby preferably said object identification properties comprise information about the object which allows identification of the object between the object database and an external database.

### Claim 2 (depends on 1)

An object database according to claim 1, whereby said set of object entries comprise further general object properties and/or derived object properties.

### Claim 3 (depends on 2)

An object database according to claim 2 wherein said derived object properties result from the analysis of said obtained object properties by algorithms and/or threshold values comparison.

### Claim 4 (depends on 1)

An object database according to claim 1, wherein said object database is stored on an external server, accessible by a user from a distinct location.

### Claim 5 (depends on 1)

An object database according to claim 1, wherein said object database is stored on an internal server.

### Claim 6 (depends on 1)

An object database according to claim 1, wherein said set of object entries are dynamic and updatable, preferably based upon feedback by user.

### Claim 7 (depends on 1)

An object database according to claim 1, wherein said object comprises a cell sample, a fluid, a body fluid, a sample comprising micro-organisms, an entomological sample or a soil sample.

### Claim 8 (depends on 7)

An object database according to claim 7, whereby said object is a cervical cell sample.

### Claim 9 (depends on 1)

An object database according to claim 1, wherein at least one object has been identified as a separate object within the sample on the basis of holographic information obtained by said DHM.

### Claim 10 (depends on 1)

An object database according to claim 1, comprising a fingerprinting algorithm for classifying an object according to its type, said algorithm taking into account at least one DHM-obtained object property.

### Claim 11

An object database updating method for improving the characterization of objects which are analyzable by a digital holographic microscope (DEM), comprising the steps of:
providing a database comprising object properties, whereby said object properties comprise obtained object properties, which comprise DHM-obtained object properties and at least one derived object property, said object database comprising at least one object entry, whereby said derived object property of said object entry is derived, preferably from said DHM-obtained object properties, using predefined algorithms and/or threshold values;
communicating said derived object property of said object entry to a user of said object database;
obtaining and/or awaiting feedback on said derived object property of said object entry from said user;
comparing said feedback with said derived object property of said object entry, hereby obtaining comparison information; and
updating said algorithms and/or threshold values according to said comparison information,
wherein said DEM-obtained object properties comprise properties derived from information acquired by a digital holographic microscope (DHM).

### Claim 12 (depends on 11)

An object database updating method according to claim 11, sending said obtained properties to said database stored on an external server.

### Claim 13 (depends on 11)

An object database updating method according to claim 11, sending said obtained properties to said database stored on an internal server.

### Claim 14 (depends on 11)

An object database updating method according to claim 11, wherein said object comprises a cell sample, a fluid, a body fluid, a sample comprising micro-organisms, an entomological sample or a soil sample.

### Claim 15 (depends on 14)

An object database updating method according to claim 14, wherein said object is a cervical cell sample.

### Claim 16 (depends on 1)

A system comprising an object database according to claim 1 and a digital holographic microscope operably connected to said database, said system arranged to update said database using an object database updating method.

### Claim 17 (depends on 1)

Computing system comprising an object database and object database updating method as according to claim 1.
