# US 2014/0195005 A1 · Osteograft implant > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2014/0195005 A1 - Document ID: US20140195005A1 - Status: Published application - Kind: A1 - Application number: 13/736,490 - Filed: 2013-01-08 - Published: 2014-07-10 - Earliest claimed: 2013-01-08 - Assignees: Warsaw Orthopedic, Inc. - Applicants: Warsaw Orthopedic, Inc. - Inventors: WILLIAM F. MCKAY - Web page: https://patentgrep.com/patent/US20140195005A1 ## CPC - A61F 2/28: Bones - A61L 27/3608: {Bone, e.g. demineralised bone matrix [DBM], bone powder} - A61L 27/50: Materials characterised by their function or physical properties {, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials} - A61F 2002/2835: {Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material} - A61F 2002/2839: {Bone plugs or bone graft dowels} - A61F 2002/30059: {differing in bone mineralization, e.g. made from both mineralized and demineralized adjacent parts} - A61F 2002/30261: {parallelepipedal} - A61F 2230/0069: cylindrical - A61F 2310/00179: Ceramics or ceramic-like structures - A61F 2310/00359: Bone or bony tissue - A61F 2310/00371: Collagen - A61L 2430/02: for reconstruction of bones; weight-bearing implants - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) ## Abstract Bone implant compositions are provided that include a body made of cortical bone extending along an axis between a first end and a second end. The body includes an outer surface configured to engage host bone of a patient and at least one recess extending transverse to the axis into the outer surface of the body configured for disposal of an insert. At least one insert made of demineralized bone is disposed in the at least one recess. ## Claims ### Claim 1 An osteograft comprising: a body comprising cortical bone extending along an axis between a first end and a second end and including an outer surface configured to engage host bone of a patient, the body including at least one recess extending transverse to the axis into the outer surface configured for disposal of an insert; and at least one insert comprising demineralized bone disposed in the at least one recess. ### Claim 2 (depends on 1) An osteograft as recited in claim 1, wherein the at least one recess extends perpendicular to the axis. ### Claim 3 (depends on 1) An osteograft as recited in claim 1, wherein the at least one insert comprises a plug. ### Claim 4 (depends on 1) An osteograft as recited in claim 1, wherein the at least one insert comprises a strip. ### Claim 5 (depends on 1) An osteograft as recited in claim 1, wherein the at least one recess has a circular cross-sectional configuration and the at least one insert has a polygonal cross-sectional configuration. ### Claim 6 (depends on 1) An osteograft as recited in claim 1, wherein the at least one insert comprises whole or partially demineralized cortical or cancellous bone and has a maximum width that is greater than a maximum width of the at least one recess, and the at least one insert is movable between a first configuration in which the at least one insert deforms to facilitate insertion into the at least one recess and a second configuration in which the at least one insert expands to retain the at least one insert in the at least one recess. ### Claim 7 (depends on 1) An osteograft as recited in claim 1, wherein the at least one insert comprises cancellous bone and has a maximum width that is greater than a maximum width of the at least one recess, and the at least one insert is movable between a first configuration in which the at least one insert deforms to facilitate insertion into the at least one recess and a second configuration in which the at least one insert expands to retain the at least one insert in the at least one recess. ### Claim 8 (depends on 1) An osteograft as recited in claim 1, wherein the at least one insert is press fit into the at least one recess. ### Claim 9 (depends on 1) An osteograft as recited in claim 1, wherein at least a portion of the body is surface demineralized to promote chemical or cohesive bonding or mechanical press fit between the body and the at least one insert. ### Claim 10 (depends on 1) An osteograft as recited in claim 1, wherein the body comprises an allograft and the at least one insert comprises bone material obtained from the patient. ### Claim 11 (depends on 1) An osteograft as recited in claim 1, wherein the at least one recess comprises a plurality of recesses that are spaced apart from one another and the at least one insert comprises a plurality of inserts. ### Claim 12 (depends on 1) An osteograft as recited in claim 1, wherein the outer surface of the body comprises an upper surface and a lower surface opposite the upper surface, and the at least one recess comprises a plurality of spaced apart recesses in the upper surface and a plurality of spaced apart recesses in the lower surface. ### Claim 13 (depends on 1) An osteograft as recited in claim 1, wherein the outer surface of the body comprises an upper surface and a lower surface opposite the upper surface, and the at least one recess comprises a plurality of spaced apart recesses disposed circumferentially about the upper surface and a plurality of spaced apart recesses disposed circumferentially about the lower surface. ### Claim 14 (depends on 1) An osteograft as recited in claim 1, wherein the outer surface of the body comprises an upper surface and a lower surface opposite the upper surface, the at least one recess comprises a plurality of spaced apart recesses in the upper surface and a plurality of spaced apart recesses in the lower surface, and each of the recesses in the upper surface is coaxial with a respective recess in the lower surface. ### Claim 15 (depends on 1) An osteograft as recited in claim 1, wherein the body comprises an upper surface and a lower surface opposite the upper surface, the body includes an inner surface defining an opening extending through the upper and lower surfaces, and the at least one recess comprises a plurality of spaced apart recesses disposed about the upper surface, a plurality of spaced apart recesses disposed about the lower surface and a plurality of spaced apart recess disposed about the inner surface. ### Claim 16 A kit comprising: an osteograft having a body comprising cortical bone extending between a first end and a second end along an axis and including an outer surface configured to engage host bone of a patient, the body including upper and lower surfaces and an inner surface defining an opening extending through the upper and lower surfaces, the upper and lower surfaces each comprising a plurality of recesses extending transverse to the axis into the outer surface, the inner surface comprising a plurality of recesses extending parallel to the axis into the inner surface, the recesses each having a circular cross-sectional configuration; a plurality of plugs comprising demineralized bone and having a polygonal cross-sectional configuration configured for disposal in one of the recesses; and/or a plurality of plugs comprising demineralized bone and having a circular cross-sectional configuration configured for disposal in one of the recesses. ### Claim 17 (depends on 18) A kit as recited in claim 18, wherein the recesses are uniform and each have a maximum width that is greater than a maximum with of the plugs having a circular cross-sectional configuration, the maximum width of the recesses being less than a maximum width of the plugs having a polygonal cross-sectional configuration. ### Claim 18 An osteograft comprising: a body comprising cortical bone extending between a first end and a second end along an axis and including an outer surface configured to engage host bone of a patient, the body comprising an upper surface and a lower surface opposite the upper surface, the body including an inner surface defining an opening extending through the upper and lower surfaces, the upper and lower surfaces each including a plurality of recesses each having a circular cross-sectional configuration and extending perpendicular to the axis into the outer surface disposed circumferentially about the upper and lower surfaces, the inner surface including a plurality of recesses each having a circular cross-sectional configuration and extending parallel to the axis; and a plurality of plugs comprising demineralized bone each having a circular cross-sectional configuration disposed in one of the recesses, wherein the inner and outer surfaces are surface demineralized before the plugs are disposed into the recesses to promote chemical or cohesive bonding or mechanical press fit between the body and the plugs.