# US 2014/0194834 A1 · Auto-Regulation System for Intraocular Pressure > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2014/0194834 A1 - Document ID: US20140194834A1 - Status: Published application - Kind: A1 - Application number: 14/150,413 - Filed: 2014-01-08 - Published: 2014-07-10 - Earliest claimed: 2013-01-08 - Assignees: University of South Florida - Inventors: Christopher Lawrence Passaglia - Web page: https://patentgrep.com/patent/US20140194834A1 ## CPC - A61F 9/00781: {Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment (drainage implants in general A61M27/002)} - A61M 1/74: {Suction control (underwater drainage A61M1/61)} - A61M 1/77: {Suction-irrigation systems (aspiration tips supplying fluids A61M1/85; specific for negative pressure wound therapy A61M1/92; combined with tracheal tubes A61M16/0463)} - A61M 1/81: {Piston pumps, e.g. syringes} - A61F 2250/0013: for adjusting fluid pressure - A61M 5/14212: {Pumping with an aspiration and an expulsion action} - A61M 5/14216: {Reciprocating piston type} - A61M 5/1422: {with double acting or multiple pistons} - A61M 5/145: using pressurised reservoirs, e.g. by means of pistons - A61M 2205/3341: stabilising pressure or flow to avoid excessive variation - A61M 2205/3344: Measuring or controlling pressure at the body treatment site - A61M 2210/0612: Eyes - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract A device and system for controlling pressure via fluid exchange in the body is presented. The device and system may be used to control intraocular eye pressure. The system is comprised of four main components: a cannula, a sensor, a controller and a pump. The system works to engage in a fluid exchange which slowly increases/decreases intraocular pressure until a desired level is reached. Once the desired level is reached, the intraocular pressure is held steady and any external pressure perturbations are removed. ## Claims ### Claim 1 A system for regulating pressure within a portion of a human or animal body, comprising: a bidirectional pump comprising: a motor, a fluid drive unit coupled to the motor, and a reservoir containing a fluid; a pressure sensor coupled to the reservoir; a cannula coupled to the reservoir such that movement of the fluid drive unit causes the fluid to flow through the cannula; and a controller operatively coupled to the pump and pressure sensor. ### Claim 2 (depends on 1) The system of claim 1, wherein the pressure sensor measures a pressure of the fluid in the reservoir. ### Claim 3 (depends on 1) The system of claim 1, wherein the controller receives a signal from the pressure sensor and causes the pump to operate in response to the signal. ### Claim 4 (depends on 3) The system of claim 3, wherein the controller compares the signal to a set point, and causes the pump to operate based on a result of the comparison. ### Claim 5 (depends on 4) The system of claim 4, wherein the controller causes the pump to withdraw fluid from the portion of the body if the signal is greater than the set point. ### Claim 6 (depends on 4) The system of claim 4, wherein the controller causes the pump to inject fluid into the portion of the body if the signal is less than the set point. ### Claim 7 (depends on 1) The system of claim 1, wherein the fluid drive unit further comprises a piston and the piston comprises a hollow space within the piston and the pressure sensor is located within the hollow space. ### Claim 8 (depends on 1) The system of claim 1, wherein the pressure sensor comprises a plurality of piezoelectric resistors electrically connected in a Wheatstone bridge configuration and mounted on a diaphragm. ### Claim 9 (depends on 1) The system of claim 1, wherein the device controls intraocular eye pressure. ### Claim 10 A system for regulating intraocular eye pressure, comprising: a bidirectional pump comprising: a motor, a piston coupled to the motor, a pressure sensor coupled to the piston, and a reservoir containing a fluid; a cannula having a first end coupled to the reservoir such that movement of the piston causes the fluid to flow through the cannula, and a second end configured for insertion into the eye such that fluid is either withdrawn or injected into the eye depending on the direction of the pump; and a controller operatively coupled to the pump and pressure sensor. ### Claim 11 (depends on 10) The system of claim 10, wherein the second end of the cannula is configured for insertion through the limbus into an anterior chamber of the eye. ### Claim 12 (depends on 11) The system of claim 11, wherein the pressure sensor measures a pressure of the fluid in the anterior chamber of the eye. ### Claim 13 (depends on 10) The system of claim 10, wherein the controller receives a signal from the pressure sensor, compares the signal to a set point, and causes the pump to operate in response to a result of the comparison. ### Claim 14 (depends on 13) The system of claim 13, wherein the controller causes the pump to withdraw fluid from the anterior chamber if the signal is greater than the set point. ### Claim 15 (depends on 13) The system of claim 13, wherein the controller causes the pump to inject fluid into the anterior chamber if the signal is less than the set point. ### Claim 16 A method for regulating intraocular eye pressure, comprising: providing a bidirectional pump, a cannula, a pressure sensor, and a controller; inserting the cannula into an anterior chamber of the eye; measuring fluid pressure within the anterior chamber and sending a signal to the controller; receiving the signal at the controller and comparing the signal to a set point; and causing the pump to operate in a first direction when the signal is below the set point and causing the pump to operate in a second direction when the signal is above the set point. ### Claim 17 (depends on 16) The method of claim 16, wherein the pump further comprises a piston and a fluid reservoir, the piston being in communication with a fluid contained in the reservoir. ### Claim 18 (depends on 17) The method of claim 17, further comprising coupling the pressure sensor to the piston. ### Claim 19 (depends on 17) The method of claim 17, wherein causing the pump to operate in the first direction injects fluid into the eye. ### Claim 20 (depends on 17) The method of claim 17, wherein causing the pump to operate in the second direction withdraws fluid from the eye.