# US 2014/0194804 A1 · Chronic Access System for Extracorporeal Treatment of Blood Including a Continuously Wearable Hemodialyzer

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- Number: US 2014/0194804 A1
- Document ID: US20140194804A1
- Status: Published application
- Kind: A1
- Application number: 14/165,983
- Filed: 2014-01-28
- Published: 2014-07-10
- Earliest claimed: 2009-06-11
- Inventors: Arnold J. Lande
- Web page: https://patentgrep.com/patent/US20140194804A1

## CPC

- A61M 1/3661: {for haemodialysis}
- A61M 1/15: {with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit}
- A61M 1/155: {with treatment-fluid pumping means or components thereof}
- A61M 1/1561: {at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil}
- A61M 1/1562: {Details of incorporated reservoirs}
- A61M 1/15632: {the filter being a dialyser}
- A61M 1/1565: {Details of valves}
- A61M 1/1566: {Means for adding solutions or substances to the treating fluid}
- A61M 1/16: with membranes
- A61M 1/1605: {Physical characteristics of the dialysate fluid}
- A61M 1/1696: {with dialysate regeneration}
- A61M 1/3622: {with a cassette forming partially or totally the blood circuit}
- A61M 1/36224: {with sensing means or components thereof}
- A61M 1/362261: {at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil}
- A61M 1/362263: {Details of incorporated filters}
- A61M 1/362265: {Details of valves}
- A61M 1/362266: {Means for adding solutions or substances to the blood}
- A61M 1/3655: {Arterio-venous shunts or fistulae}
- A61M 1/3672: {Means preventing coagulation}
- A61M 1/3675: {Deactivation}
- A61M 1/36225: {with blood pumping means or components thereof}
- A61M 2205/123: with incorporated reservoirs
- A61M 2205/126: with incorporated membrane filters
- A61M 2205/128: with incorporated valves
- A61M 2205/3317: Electromagnetic, inductive or dielectric measuring means
- A61M 2205/3324: PH measuring means
- A61M 2205/8206: battery-operated
- A61M 2209/088: on the body
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

A patient wearable, continuously operating extracorporeal pump apparatus which accesses the patient's arterial venous pressure differential by applying external pressure to a subcutaneous graft that has been cannualized to modulate blood flow through an extracorporeal circuit and to drive the pump for delivering a medicament, such as an anticoagulant, to the site of an intravenous cannula to prevent clogging thereof and also to move a dialysate through a circuit, including a dialyzer and a dialysate rejuvenating cartridge, whereby kidney failure can be treated without recourse to prior art hemodialysis machines found in most treatment facilities. With slight modification, the present invention can be used to remove excess fluids from CHF patients, to remove toxins from the blood in those suffering from liver failure and to facilitate administration of insulin to diabetics and/or glucose to those having hypoglycemia.

## Claims

### Claim at position 1

1-51. (canceled)

### Claim 52

A method for obtaining access to a patient's arteriovenous pressure differential and extracorporeal blood flow comprising the steps of:
(a) selecting a venous segment in the patient's forearm and debranching the selected venous segment and occluding and transecting the distal end thereof;
(b) anastomosing the remaining end portion of the transected debranched vein to a selected artery in the patient's forearm, creating a fistula;
(c) inserting a first needle cannula percutaneously into the debranched vein segment for accessing AV pressure differential and extracorporeal blood flow and inserting a second needle percutaneously into the debranched vein for return of the extracorporeal blood flow to the patient's circulation; and
(d) sequentially applying compression to the forearm between the first and second needle cannulas sufficient to substantially occlude blood flow through the debranched vein segment and thereby establishing the pressure whereby when the compression is being applied, the needle cannula is exposed to arterial pressure and when released, the cannula is exposed to venous pressure.

### Claim 53

A method for obtaining therapeutic anticoagulation of an extracorporeal circuit comprising the steps of:
(a) providing the a medical device having a reservoir containing an anti-coagulant, the reservoir being, in fluid communication with at least one percutaneous cannula via a compressible tube segment and an extracorporeal peristaltic pump coacting with the compressible tube segment for moving the anti-coagulant through the at least one cannula;
(b) percutaneously inserting the cannula into a debranched vein segment or a VFG;
(c) periodically compressing and releasing the debranched vein segment or the VFG to expose the blood exiting and entering said cannula to arterial pressure and venous pressure; and whereby
the pump is activated based on the difference between the arterial pressure and the venous pressure of the blood entering and exiting the cannula.

### Claim 54 (depends on 53)

The method of claim 53 and further including the steps of:
(a) providing a dialyzer having a plurality of semi-permeable membranes within an outer housing;
(b) connecting the dialyzer to the cannula such that blood flows through a ventricle to power the pump and thence over a first surface of the plurality of membranes;
(c) the pump circulating dialysate through the housing and over a second surface of the membranes in proportion to the flow rate of the blood through the dialyzer; and
(d) providing a dialysate rejuvenating cartridge using the pump to move dialysate through said cartridge.

### Claim 55

(canceled)

### Claim 56 (depends on 54)

The method of claim 54 and further including the step of:
(a) providing an ameroid for blocking dialysate flow through the cartridge after a predetermined degree of use of the cartridge.