# US 2014/0194756 A1 · Biological rhythm disturbance degree calculating device, biological rhythm disturbance degree calculating system, biological rhythm disturbance degree calculating method, program, and recording medium > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2014/0194756 A1 - Document ID: US20140194756A1 - Status: Published application - Kind: A1 - Application number: 14/117,691 - Filed: 2012-05-14 - Published: 2014-07-10 - Earliest claimed: 2011-05-24 - Assignees: Sony Corporation - Inventors: Naoya Sazuka - Web page: https://patentgrep.com/patent/US20140194756A1 ## CPC - A61B 5/0002: {Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network (endoradiosondes A61B5/07)} - A61B 5/01: Measuring temperature of body parts {; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue} (clinical contact thermometers G01K13/20) - A61B 5/024: Measuring pulse rate or heart rate - A61B 5/1118: {Determining activity level} - A61B 5/4857: {Indicating the phase of biorhythm} - A61B 5/7282: {Event detection, e.g. detecting unique waveforms indicative of a medical condition (cough events A61B5/0823; seizures A61B5/4094; sleep apnoea A61B5/4818)} - A61B 5/742: {using visual displays (displays for heart-related electrical signals, e.g. ECG, A61B5/339)} - G16H 50/30: for calculating health indices; for individual health risk assessment - A61B 5/11: Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb {(A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721)} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA ## Abstract There is provided a biological rhythm disturbance degree calculating device, including a physiological index time series data acquiring unit which acquires time series data of a physiological index calculated from a biomedical signal of a subject, a calculation period deciding unit which decides a calculation period which is a time length corresponding to substantially a half of a cycle with which daily-life physiological index time series data calculated from the biomedical signal measured in daily life fluctuates, a calculating unit which calculates, during the calculation period, a phase shift amount between inspected physiological index time series data calculated from the biomedical signal measured during an inspection and the daily-life physiological index time series data, and a disturbance degree deciding unit which decides a disturbance degree of a biological rhythm during the inspection of the subject based on the phase shift amount. ## Claims ### Claim 1 A biological rhythm disturbance degree calculating device, comprising: a physiological index time series data acquiring unit which acquires time series data of a physiological index calculated from a biomedical signal of a subject; a calculation period deciding unit which decides a calculation period based on first physiological index time series data calculated from the biomedical signal measured at a first timing; a calculating unit which calculates, during the calculation period, a phase shift amount between second physiological index time series data calculated from the biomedical signal measured at a second timing and the first physiological index time series data; and a disturbance degree deciding unit which decides a disturbance degree of a biological rhythm at the second timing of the subject based on the phase shift amount. ### Claim 2 (depends on 1) The biological rhythm disturbance degree calculating device according to claim 1, wherein the calculating unit calculates the shift amount based on a ratio between a first feature quantity corresponding to the second physiological index time series data which has a value larger than an average value of the first physiological index time series data, and a second feature quantity corresponding to the second physiological index time series data which has a value smaller than the average value. ### Claim 3 (depends on 2) The biological rhythm disturbance degree calculating device according to claim 2, wherein the first feature quantity is an area of a region surrounded by a waveform of the second physiological index time series data which has a larger value than the average value and by a straight line indicating the average value, and wherein the second feature quantity is an area of a region surrounded by a waveform of the second physiological index time series data which has a smaller value than the average value and by the straight line indicating the average value. ### Claim 4 (depends on 2) The biological rhythm disturbance degree calculating device according to claim 2, wherein the first feature quantity is a time length of a period during which the second physiological index time series data has a larger value than the average value, and wherein the second feature quantity is a time length of a period during which the second physiological index time series data has a smaller value than the average value. ### Claim 5 (depends on 1) The biological rhythm disturbance degree calculating device according to claim 1, wherein the calculation period deciding unit sets the calculation period to a period between a first reference time point at which a value of the first physiological index time series data changes from the average value or less to the average value or more, and a second reference time point at which the value of the first physiological index time series data changes from the average value or more to the average value or less. ### Claim 6 (depends on 5) The biological rhythm disturbance degree calculating device according to claim 5, wherein the calculating unit sets a ratio of the first feature quantity as the phase shift amount during a first calculation period ranging from the first reference time point to the second reference time point, and further sets a ratio of the second feature quantity as the phase shift amount during a second calculation period ranging from the second reference time point to the first reference time point. ### Claim 7 (depends on 6) The biological rhythm disturbance degree calculating device according to claim 6, wherein the disturbance degree deciding unit sets any one of the phase shift amount during the first calculation period, the phase shift amount during the second calculation period, and an average value of the phase shift amount during the first calculation period and the phase shift amount during the second calculation period, as the disturbance degree. ### Claim 8 (depends on 7) The biological rhythm disturbance degree calculating device according to claim 7, further comprising: an activity time zone information acquiring unit which acquires a time shift of an activity time zone of the subject which leads to the disturbance of the biological rhythm, and a cause of a shift of the activity time zone, wherein the disturbance degree deciding unit sets an average value of the phase shift amount during the first calculation period and the phase shift amount during the second calculation period as the disturbance degree when the cause of the shift of the activity time zone is an eastward travel across zones with a time difference. ### Claim 9 (depends on 8) The biological rhythm disturbance degree calculating device according to claim 8, further comprising: a history information acquiring unit which acquires history information of the disturbance degree; and a prediction information generating unit which predicts the disturbance degree based on the time shift and the history information extracted based on the cause of the shift. ### Claim 10 (depends on 9) The biological rhythm disturbance degree calculating device according to claim 9, wherein the history information acquiring unit acquires history information of another subject who is similar in reference information to the subject, when there are no pieces of history information which match in the time shift and the cause of the shift within the history information on the subject. ### Claim 11 (depends on 8) The biological rhythm disturbance degree calculating device according to claim 8, wherein the activity time zone information acquiring unit detects that the cause of the shift of the activity time zone is a travel across zones with a time difference, based on a change in positional information of the subject, and further detects corresponding time difference. ### Claim 12 (depends on 8) The biological rhythm disturbance degree calculating device according to claim 8, wherein the activity time zone information acquiring unit estimates the time shift of the activity time zone of the subject based on a detection value of a motion sensor which detects motion of the subject. ### Claim 13 (depends on 5) The biological rhythm disturbance degree calculating device according to claim 5, wherein the biomedical signal is a signal having a biological rhythm of a circadian rhythm, and wherein the calculation period deciding unit sets the calculation period to a time period when the first reference time point is set to a time point 6 hours prior to a peak time point in the first physiological index time series data and when the second reference time point is set to a time point 6 hours behind the peak time point. ### Claim 14 (depends on 1) The biological rhythm disturbance degree calculating device according to claim 1, wherein the biomedical signal is a signal indicating a value of a core temperature. ### Claim 15 (depends on 1) The biological rhythm disturbance degree calculating device according to claim 1, wherein the biomedical signal is a signal indicating a pulse wave and the physiological index is one of a pulse rate and an augmentation index (AI) value. ### Claim 16 (canceled) ### Claim 17 A classifying device comprising: an information acquiring unit which acquires an average value of time series data of a physiological index calculated from a daily-life biomedical signal with respect to a plurality of subjects, and a first reference time point and a second reference time point based on the average value; and a classifying unit which classifies a biological rhythm of a specific subject into any one type among a morning type, a night type, and an average type, based on information acquired by the information acquiring unit. ### Claim 18 A biological rhythm disturbance degree calculating system comprising: a user device including an estimation condition input unit, to which estimation conditions including a time shift of an activity time zone, and a cause of a shift of the activity time zone are input, and a transmitting unit which transmits the estimation conditions to a server; and the server including an acquiring unit which acquires a disturbance degree of a biological rhythm with respect to a plurality of subjects, the disturbance degree of the biological rhythm being calculated based on a phase shift amount between second physiological index time series data calculated from a biomedical signal measured at a second timing and first physiological index time series data, during a calculation period decided based on the first physiological index time series data calculated from the biomedical signal measured at a first timing, an estimating unit which estimates the disturbance degree under the estimation conditions using the disturbance degrees with respect to the plurality of subjects, and a display screen generating unit which generates a display screen including information on the estimated disturbance degree and which provides the user device with the display screen. ### Claim 19 A biological rhythm disturbance degree calculating method, comprising: acquiring physiological index time series data calculated from a biomedical signal of a subject; deciding a calculation period based on first physiological index time series data calculated from the biomedical signal measured at first timing; calculating, during the calculation period, a phase shift amount between second physiological index time series data calculated from the biomedical signal measured at a second timing and the first physiological index time series data; and deciding a disturbance degree of a biological rhythm during the second timing of the subject based on the phase shift amount. ### Claim 20 A program causing a computer to execute a biological rhythm calculating method comprising: acquiring physiological index time series data calculated from a biomedical signal of a subject; deciding a calculation period based on first physiological index time series data calculated from the biomedical signal measured at a first timing; calculating, during the calculation period, a phase shift amount between second physiological index time series data calculated from the biomedical signal measured at a second timing and the first physiological index time series data; and deciding a disturbance degree of a biological rhythm at the second timing of the subject based on the phase shift amount. ### Claim 21 A computer-readable recording medium storing a program which causes a computer to execute a biological rhythm disturbance degree calculating method comprising: acquiring physiological index time series data calculated from a biomedical signal of a subject; deciding a calculation period based on first physiological index time series data calculated from the biomedical signal measured at a first timing; calculating, during the calculation period, a phase shift amount between second physiological index time series data calculated from the biomedical signal measured at a second timing and the first physiological index time series data; and deciding a disturbance degree of a biological rhythm at the second timing of the subject based on the phase shift amount. ### Claim 22 (depends on 1) A biological rhythm disturbance degree calculating device according to claim 1, wherein the calculation period deciding unit calculates, as the calculation period, a period having a time length which is substantially a half of a cycle with which the first physiological index time series data fluctuates;