# US 2014/0194586 A1 · Method for treatment of synthetic rubber products, a system for treatment, the resulting rubber products, and use of a method to reduce type iv allergenicity of rubber products > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2014/0194586 A1 - Document ID: US20140194586A1 - Status: Published application - Kind: A1 - Application number: 14/122,064 - Filed: 2012-05-24 - Published: 2014-07-10 - Earliest claimed: 2011-05-25 - Assignees: Budev B.V. - Inventors: Michiel Inno Paping; Karen-Marlies Schenck - Web page: https://patentgrep.com/patent/US20140194586A1 ## CPC - C08C 3/02: Purification - C08C 1/04: Purifying; Deproteinising - C08C 2/02: Purification - C08C 2/04: Removal of catalyst residues - C08J 7/02: with solvents, e.g. swelling agents - C08J 2321/02: Latex - C08C: TREATMENT OR CHEMICAL MODIFICATION OF RUBBERS - C08J: WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H (working, e.g. shaping, of plastics B29) ## Abstract The present invention relates to a method of reducing type IV rubber allergy of synthetic rubber latex products caused by chemical residues remaining after manufacture of the synthetic rubber products by reducing levels of chemical residues found for said products, said method comprising the steps of: subjecting said products to a wash in a strong alkaline solution to remove the chemical residues remaining after manufacture of the rubber latex products, and a system for reducing type IV allergenicity of synthetic rubber products caused by chemical residues remaining after manufacture of the synthetic rubber latex products by reducing residual levels of chemical residues found for said products, and a product, such as a glove, manufactured from synthetic rubber latex processed in accordance with the method and/or using the system. Further the invention relates to a use of a method of subjecting products to said wash and raising the temperature to at least 100C to remove the chemical residues remaining after manufacture of the synthetic rubber products. ## Claims ### Claim at position 1 1-16. (canceled) ### Claim 17 A method of reducing type IV rubber allergy of synthetic rubber products caused by chemical residues, in particular residual accelerators and/or antioxidants, remaining after manufacturing of rubber products by reducing levels of chemical residues found for said products, said method comprising the steps of: subjecting said rubber products to a wash in a strong alkaline solution to remove the chemical residues remaining after manufacture of the synthetic rubber products; and raising the temperature of the strong alkaline solution to at least 100° C., and keeping the strong alkaline solution in a fluid phase without evaporation or boiling and/or freeing salty alkalines. ### Claim 18 (depends on 17) The method of claim 17, comprising: raising the temperature of the strong alkaline solution to 110° C. or higher and more preferably to approximately 118° C. ### Claim 19 (depends on 17) The method of claim 17, further comprising: pressurizing the strong alkaline solution to prevent evaporation of at least water in the strong alkaline solution. ### Claim 20 (depends on 18) The method of claim 18, comprising: pressurizing the strong alkaline solution to at least 1.5 atm., preferably at least 2.0 atm. ### Claim 21 (depends on 19) The method of claim 19, comprising: pressurizing the strong alkaline solution to at least 1.5 atm., preferably at least 2.0 atm. ### Claim 22 (depends on 17) The method of claim 17, further comprising adding an additive to the strong alkaline solution to raise the boiling point of the alkaline solution and/or to prevent freeing salty alkalines. ### Claim 23 (depends on 17) The method of claim 17, wherein said strong alkaline solution has a pH of 10 or more, more preferably a pH of 14. ### Claim 24 (depends on 17) The method of claim 17, wherein the chemical residue is at least of the compounds from the group, comprising BHA, BHT, DPG, DPT, MBT, TMTD, ZDBC, ZDEC, ZDMC, ZMBI, ZMBT and ZPMC. ### Claim 25 (depends on 17) The method of claim 17, wherein said strong alkaline solution is a solution of NaOH or KOH in a concentration of preferably 0.01M or higher, more preferably a concentration of 1 M. ### Claim 26 (depends on 17) The method of claim 17, wherein said strong alkaline solution comprises at least one nucleofile from the group, which at least comprises H2O, OH, CH3—CH2—O—, I—and CN—. ### Claim 27 (depends on 17) The method of claim 17, wherein the step of subjecting said products to a wash in a strong alkaline solution is maintained for at least five minutes, more preferably at least one hour. ### Claim 28 (depends on 17) The method of claim 17, further comprising powdering the product, for instance with talcum powder or starch. ### Claim 29 (depends on 17) System for executing the method according to claim 17 to reduce type IV allergenicity of synthetic rubber products caused by chemical residues, in particular residual accelerators and/or anti-oxidants, remaining after manufacture of the rubber products by reducing levels of chemical residues found for said products, said system comprising: a vessel comprising a strong alkaline solution to remove chemical residues remaining after manufacture of the synthetic rubber products. ### Claim 30 (depends on 29) The system of claim 29, where the vessel is a pressure vessel. ### Claim 31 (depends on 17) A product, such as a glove or condom, manufactured from synthetic rubber and subjected to a method as defined in claim 17, the product after subjection to the method exhibiting a lower level of chemical residues, such as accelerators and/or anti-oxidants, than 10.0 μg/gram, more preferably lower than 7.0 μg/gram, even more preferably lower than 4.0 μg/gram, and most preferably lower than 2.0 μg/gram. ### Claim 32 (depends on 31) The product as defined in claim 31, wherein the product is manufactured from at least one synthetic rubber from the group of materials comprising: nitril, vynil en polypropylene, or other materials like poly-isoprene, and combinations of such synthetic materials. ### Claim 33 Use of a method of cleaning rubber products, comprising the steps of: subjecting said rubber products to a wash in a strong alkaline solution; and raising the temperature of the strong alkaline solution to at least 100° C., and keeping the strong alkaline solution in a fluid phase without evaporation or boiling and/or freeing salty alkalines, in processing of synthetic rubber products to reduce type IV rubber allergy of the synthetic rubber products, which is caused by chemical residues, in particular residual accelerators and/or antioxidants employed during production of the synthetic rubber products and of which chemical residues remain after manufacture of the rubber products, by removing the chemical residues remaining after manufacture of the synthetic rubber products.