# US 2014/0194529 A1 · Usage of natural compound for treating inflammation and cancer

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- Number: US 2014/0194529 A1
- Document ID: US20140194529A1
- Status: Published application
- Kind: A1
- Application number: 14/149,820
- Filed: 2014-01-08
- Published: 2014-07-10
- Earliest claimed: 2013-01-10
- Assignees: Hong Kong Baptist University
- Applicants: Hong Kong Baptist University
- Inventors: Hongxi XU; Dandan ZHANG; Hong ZHANG; Kaixian CHEN; Zhaoxiang BIAN; Chengyuan LIN; Dajian YANG; Shilin CHEN; Aiping LU; Albert Sun Chi CHAN
- Web page: https://patentgrep.com/patent/US20140194529A1

## CPC

- A61K 31/122: having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A61K 36/38: Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)

## Abstract

This invention relates to the use of a compound from natural sources for therapeutic uses. More particularly, it relates to a compound, Garcimultiflorone E, naturally occurring in the plant of Garcinia esculenta Y. H. Li which has potent anti-inflammation and anti-cancer effect.

## Claims

### Claim 1

A composition for treating cancer comprising an effective amount of a compound with the chemical structure of

### Claim 2 (depends on 1)

The composition according to claim 1 wherein said compound comprising Garcimultiflorone E.

### Claim 3 (depends on 1)

The composition according to claim 1 wherein said compound is extracted from a natural plant.

### Claim 4 (depends on 3)

The composition according to claim 3 wherein the natural plant is from a genus Garcinia.

### Claim 5 (depends on 4)

The composition according to claim 4 wherein the genus Garcinia comprising a subspecies of Garcinia esculenta Y. H. Li.

### Claim 6 (depends on 1)

The composition according to claim 1 wherein the cancer comprising breast cancer and liver cancer.

### Claim 7

A composition for treating inflammation comprising an effective amount of a compound with the chemical structure of

### Claim 8 (depends on 7)

The composition according to claim 7 wherein said compound comprising Garcimultiflorone E.

### Claim 9 (depends on 7)

The composition according to claim 7 wherein said compound is extracted from a natural plant.

### Claim 10 (depends on 9)

The composition according to claim 9 wherein the natural plant is from a genus Garcinia.

### Claim 11 (depends on 10)

The composition according to claim 10 wherein the genus Garcinia comprising a subspecies of Garcinia esculenta Y. H. Li.

### Claim 12 (depends on 1)

A use of the composition according to claim 1 for manufacture of a medicament for treatment of cancer.

### Claim 13 (depends on 7)

A use of the composition according to claim 7 for manufacture of a medicament for treatment of inflammation.

### Claim 14 (depends on 1)

A method of treating cancer comprising administering a composition of claim 1, wherein the cancer comprising breast or liver cancer.

### Claim 15 (depends on 7)

A method of treating inflammation comprising administering a composition of claim 7.

### Claim 16 (depends on 14)

The method according to claim 14 wherein the effective amount is about 10 μM.

### Claim 17 (depends on 15)

The method according to claim 15 wherein the effective amount is about 10 μM.