# US 2014/0194511 A1 · Dietary formulations and methods for treatment of inflammation and other disorders

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- Number: US 2014/0194511 A1
- Document ID: US20140194511A1
- Status: Published application
- Kind: A1
- Application number: 14/148,197
- Filed: 2014-01-06
- Published: 2014-07-10
- Earliest claimed: 2007-05-25
- Assignees: Beth Israel Deaconess Medical Center, Inc.; Children's Medical Center Corporation
- Applicants: Beth Israel Deaconess Medical Center, Inc.; Children's Medical Center Corporation
- Inventors: Mark PUDER; Bruce BISTRIAN
- Web page: https://patentgrep.com/patent/US20140194511A1

## CPC

- A23D 9/013: Other fatty acid esters, e.g. phosphatides
- A23L 33/12: Fatty acids or derivatives thereof
- A61K 31/202: having three or more double bonds, e.g. linolenic (eicosanoids, e.g. leukotrienes A61K31/557)
- A61K 31/23: of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61P 3/00: Drugs for disorders of the metabolism (of the blood or the extracellular fluid A61P7/00)
- A61P 3/02: Nutrients, e.g. vitamins, minerals
- A61P 29/00: Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P 35/00: Antineoplastic agents
- A61P 39/00: General protective or antinoxious agents
- A61P 43/00: Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A23V 2002/00: Food compositions, function of food ingredients or processes for food or foodstuffs
- A23D: EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS (preservation thereof A23B20/00; production, refinement or preservation of animal or vegetable fats or oils C11B, C11C)
- A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B)
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A23V: INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION

## Abstract

Dietary formulations in the form of an oil emulsion providing total enteral or parenteral nutrition, or in the form of food oil suitable for oral administration is provided. The formulations include about 2-60% by calories of a C20 or longer omega-3 fatty acid and about 0.05% to 1% by calories of arachidonic acid, where the formulation provides less than 1% of total calories from linoleic acid and alpha-linolenic acid, and where the fatty acids provide 5-60% of the total calories of said dietary formulation. Methods for treatment of diseases and disorders using the dietary formulations are also provided.

## Claims

### Claim 1

A dietary formulation for total enteral or parenteral nutrition, or a dietary supplement in the form of food oil that is suitable for oral administration, comprising:
about 2-60% by calories of a C20 or longer omega 3 fatty acid; and
about 0.05% to 1% by calories of arachidonic acid;
wherein the formulation or supplement provides less than 1% of total calories from linoleic acid and alpha-linolenic acid, and wherein said fatty acids provide 5-60% of the total calories of said dietary formulation.