# US 2014/0194339 A1 · Novel quinazoline compounds and their use in perfume compositions

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- Number: US 2014/0194339 A1
- Document ID: US20140194339A1
- Status: Published application
- Kind: A1
- Application number: 14/203,993
- Filed: 2014-03-11
- Published: 2014-07-10
- Earliest claimed: 2011-02-15
- Assignees: International Flavors & Fragrances Inc.
- Applicants: International Flavors & Fragrances Inc.
- Inventors: Michael G. Monteleone; Robert P. Belko; Franc T. Schiet; Paul D. Jones; Anthony T. Levorse, JR.
- Web page: https://patentgrep.com/patent/US20140194339A1

## CPC

- C11B 9/0092: {containing only N as heteroatom}
- A61K 8/4953: {containing pyrimidine ring derivatives, e.g. minoxidil}
- A61Q 13/00: Formulations or additives for perfume preparations (essential oils or perfumes per se C11B9/00)
- C07D 239/26: with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D 239/74: with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
- C11D 3/28: Heterocyclic compounds containing nitrogen in the ring
- C11D 3/50: Perfumes
- A61K 2800/10: General cosmetic use
- A61L 9/01: Deodorant compositions {(compositions released by contact with a liquid A61L9/05)}
- A61Q 15/00: Anti-perspirants or body deodorants (deodorisation of air A61L9/00)
- C11B: PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES (drying-oils C09F)
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- C07D: HETEROCYCLIC COMPOUNDS (macromolecular compounds C08)
- C11D: DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)

## Abstract

The present invention relates to novel quinazoline compounds and their use in perfume compositions. The novel quinazoline compounds of the present invention are represented by the following formula: an isomer or a mixture of isomers thereof, wherein the broken line represents a single or double bond.

## Claims

### Claim 1

A method of improving, enhancing or modifying a fragrance formulation through the addition of an olfactory acceptable amount of a compound 6,7,8,9-tetrahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline.

### Claim 2 (depends on 2)

The method of claim 2, wherein the olfactory acceptable amount is from about 0.005 to about 50 weight percent of the fragrance formulation.

### Claim 3 (depends on 2)

The method of claim 2, wherein the olfactory acceptable amount is from about 0.5 to about 25 weight percent of the fragrance formulation.

### Claim 4 (depends on 2)

The method of claim 2, wherein the olfactory acceptable amount is from about 1 to about 10 weight percent of the fragrance formulation.