# US 2014/0193893 A1 · Genetic test system > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2014/0193893 A1 - Document ID: US20140193893A1 - Status: Published application - Kind: A1 - Application number: 14/235,869 - Filed: 2012-05-30 - Published: 2014-07-10 - Earliest claimed: 2011-08-01 - Assignees: Hitachi High-Technologies Corporation - Inventors: Masato Ishizawa; Yoshiyuki Shoji - Web page: https://patentgrep.com/patent/US20140193893A1 ## CPC - C12Q 1/6844: Nucleic acid amplification reactions - G01N 35/04: Details of the conveyor system {(G01N35/021 - G01N35/028 take precedence)} - G01N 2035/00346: {Heating or cooling arrangements} - C12Q: MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS (immunoassay G01N33/53); COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES - G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q) ## Abstract There is provided a genetic test system provided with a dispensing means for dispensing a sample and a reagent to a reaction vessel and a vessel conveyance means for conveying the reaction vessel. The system further includes a plurality of nucleic acid amplification detection units, each including a temperature control means for accommodating a plurality of reaction vessels and performing temperature control for each accommodated position of the reaction vessel, a temperature monitoring means for monitoring a value of temperature to be controlled of the reaction vessel, and a light emission measurement means for measuring light emission of reaction liquid in the reaction vessel. At least one of the nucleic acid amplification detection units individually has a vessel conveyance means different from the above-mentioned vessel conveyance means. ## Claims ### Claim 1 A genetic test system provided with a dispensing means for dispensing a sample and a reagent to a reaction vessel and a vessel conveyance means for conveying the reaction vessel, the system comprising: a plurality of nucleic acid amplification detection units each including a temperature control means for accommodating a plurality of reaction vessels and performing temperature control for each accommodated position of the reaction vessel, a temperature monitoring means for monitoring a value of temperature to be controlled of the reaction vessel, and a light emission measurement means for measuring light emission of reaction liquid in the reaction vessel, wherein at least one of the nucleic acid amplification detection units individually has a vessel conveyance means different from the above-mentioned vessel conveyance means. ### Claim 2 (depends on 1) The genetic test system according to claim 1, comprising a vessel path along which the reaction vessel is moved between the nucleic acid amplification detection units. ### Claim 3 (depends on 1) The genetic test system according to claim 1, wherein an arbitrary number of the nucleic acid amplification detection units can be added. ### Claim 4 (depends on 3) The genetic test system according to claim 3, wherein the additional nucleic acid amplification detection units each individually have the vessel conveyance means. ### Claim 5 (depends on 1) The genetic test system according to claim 1, wherein throughput defined by a heating/cooling means, the temperature monitoring means, the light emission measurement means is higher in the additional device than in a genetic test device and abrupt functional extension can be achieved. ### Claim 6 (depends on 1) The genetic test system according to claim 1, wherein throughput defined by a heating/cooling means, the temperature monitoring means, the light emission measurement means is lower in the additional device than in a genetic test device and gradual functional extension can be achieved. ### Claim 7 (depends on 1) The genetic test system according to claim 1, wherein only one type of combination of a measurement wavelength and an excitation wavelength of the plurality of provided light emission measurement means exists in the genetic test system. ### Claim 8 (depends on 1) The genetic test system according to claim 1, wherein a plurality of types of combinations of measurement wavelengths or excitation wavelengths of the plurality of provided light emission measurement means exists in the genetic test system, and the combination of the measurement-wavelength and excitation-wavelength is the same in each nucleic acid amplification detection unit. ### Claim 9 (depends on 1) The genetic test system according to claim 1, wherein a plurality of types of combinations of measurement wavelengths or excitation wavelengths of the plurality of provided light emission measurement means exist in the genetic test system, and the plurality of combinations are the same in each nucleic acid amplification detection unit. ### Claim 10 (depends on 1) The genetic test system according to claim 1, wherein a plurality of types of combinations of measurement wavelengths or excitation wavelengths of the plurality of provided light emission measurement means exist in the genetic test system, and the plurality of combinations differ for each nucleic acid amplification detection unit. ### Claim 11 (depends on 1) The genetic test system according to claim 1, wherein only one test item defined by the plurality of provided light emission measurement means exists in the genetic test system, and the test item is the same between the genetic test device and additional device. ### Claim 12 (depends on 1) The genetic test system according to claim 1, wherein a plurality of types of test items defined by the plurality of provided light emission measurement means exist in the genetic test system, and the same test item is set in the genetic test device or in the additional device, and by specifying a device that performs measurement for each test item in a single system, data reproducibility can be significantly increased. ### Claim 13 (depends on 1) The genetic test system according to claim 1, wherein a plurality of types of test items defined by the plurality of provided light emission measurement means exist in the genetic test system, and the same combination of the plurality of types of the test items can be set in the genetic test device or additional device to allow a fail-safe function to be achieved. ### Claim 14 (depends on 1) The genetic test system according to claim 1, wherein a plurality of types of test items defined by the plurality of provided light emission measurement means exist in the genetic test system, and a combination of the plurality of types of the test items can be made different between the genetic test device and the additional device, and by specifying a device that performs measurement for each test item in a single system, multiple analysis can be made in a single system, and data reproducibility can be significantly increased. ### Claim 15 (depends on 1) The genetic test system according to claim 1, comprising a preprocessing extraction device serving as a means for extracting a specimen to be measured. ### Claim 16 (depends on 1) The genetic test system according to claim 1, wherein an inlet for a specimen to be measured is provided in each of the genetic test device and a plurality of the preprocessing extraction device, through which the specimen can be put in each of the devices. ### Claim 17 (depends on 1) The genetic test system according to claim 1, wherein when an abnormality occurs in a specific part of the temperature monitoring means or the light emission measurement means during a processing operation for the specimen to be measured to disable further continuation of the processing for the specimen to be measured in a given test device, a vessel accommodating the specimen to be measured is conveyed to another device in the test system according to a previously defined rule so as to complete the processing operation for the specimen to be measured. ### Claim 18 (depends on 1) The genetic test system according to claim 1, comprising a clogging detection means for detecting a foreign matter in a vessel accommodating a specimen extracted by the preprocessing extraction device, wherein when the abnormality is detected by the clogging detection means, subsequent processing to be applied to the extracted specimen is automatically stopped. ### Claim 19 (depends on 1) The genetic test system according to claim 1, wherein the number of specimens to be processed is scheduled according to the measurement item so as to average availability of the entire system to automatically maintain an optimum operating state.