# US 2014/0193776 A1 · Body made of bone substitute material and method for production

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- Number: US 2014/0193776 A1
- Document ID: US20140193776A1
- Status: Published application
- Kind: A1
- Application number: 14/238,169
- Filed: 2012-08-08
- Published: 2014-07-10
- Earliest claimed: 2011-08-11
- Assignees: regenHU AG
- Inventors: Marc Thurner; Michael Kuster
- Web page: https://patentgrep.com/patent/US20140193776A1

## CPC

- A61L 27/56: Porous materials, {e.g. foams or sponges}
- A61B 17/8625: {Shanks, i.e. parts contacting bone tissue}
- A61B 17/866: {Material or manufacture}
- A61C 8/0012: {characterised by the material or composition, e.g. ceramics, surface layer, metal alloy (use of specific materials A61K6/00)}
- A61C 8/0013: {with a surface layer, coating}
- A61F 2/28: Bones
- A61L 31/146: {Porous materials, e.g. foams or sponges}
- A61B 17/8685: {comprising multiple separate parts}
- A61B 17/8695: {Washers (surrounding screw head in plate hole A61B17/8047, between bone plate and bone A61B17/8028)}
- A61B 2017/8655: {with special features for locking in the bone}
- A61F 2002/2835: {Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material}
- A61F 2310/00179: Ceramics or ceramic-like structures
- A61L 2430/02: for reconstruction of bones; weight-bearing implants
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61C: DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE (non-driven toothbrushes A46B; {tongue scrapers A61B17/24;} preparations for dentistry A61K6/00; preparations for cleaning the teeth or mouth A61K8/00, A61Q11/00)
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)

## Abstract

The invention relates to a biocompatible body to be implanted into a cavity of a bone, comprising a main structure made of a bone substitute material. According to the invention, the body has a connecting element, said connecting element being embedded at least partially in the main structure of the body.

## Claims

### Claim 1

A biocompatible body (1) for implanting into a cavity of a bone, comprising:
a main structure made from a bone substitute material, characterized in that the body has a connection element, and the connection element is at least partly embedded in the main structure of the body.

### Claim 2 (depends on 1)

The biocompatible body according to claim 1, wherein the connection piece has a head, which is embedded in the main structure of the body such that the main structure encloses the head of the connection piece like a collar.

### Claim 3 (depends on 1)

The biocompatible body according to claim 1, wherein the connection element has an anchoring segment, while the connection element is embedded by the anchoring segment in form-fitting manner in the main structure of the body.

### Claim 4 (depends on 1)

The biocompatible body according to claim 1, characterized in that the connection element has a receiving opening for a connection or terminating element.

### Claim 5 (depends on 1)

The biocompatible body according to claim 1, wherein the receiving opening is accessible from outside the main structure of the body for the connection or terminating element.

### Claim 6 (depends on 3)

The biocompatible body according to claim 3, wherein the anchoring segment is shaped so that it is embedded in the main structure secure against twisting.

### Claim 7 (depends on 3)

The biocompatible body according to claim 3, wherein the anchoring segment of the connection element has an undercut, by which the connection element engages with the main structure.

### Claim 8 (depends on 1)

The biocompatible body according to claim 1, wherein the connection element is fashioned as a single piece.

### Claim 9 (depends on 1)

The biocompatible body according to claim 1, wherein the connection element is made of ceramics, metal, polymer or plastic.

### Claim 10 (depends on 1)

The biocompatible body according to claim 1, wherein the main structure of bone substitute material is osteoconductive.

### Claim 11 (depends on 1)

The biocompatible body according to claim 1, wherein the main structure of bone substitute material has voids fortified with an osteoinductive compound and/or pharmaceutical or bioactive products.

### Claim 12 (depends on 1)

The biocompatible body according to claim 1, wherein the main structure has a macroporous, interconnected structure, having a gyroid or gyroid-like structure.

### Claim 13 (depends on 1)

The biocompatible body according to claim 1, wherein the shape of the main structure is adapted to the shape of the cavity in the bone.

### Claim 14 (depends on 1)

The biocompatible body according to claim 1, wherein it has a second main structure of a biocompatible material, preferably a cartilage substitute material or soft tissue substitute.

### Claim 15

A method for production of a biocompatible body comprising:
preparing a connection element;
emplacing a main structure of bone substitute material, so that the connection element is embedded in the main structure of bone substitute material.

### Claim 16 (depends on 15)

The method according to claim 15, wherein the emplacing of the main structure further comprises:
a) depositing a layer of the main structure of bone substitute material in lines spaced apart from each other and preferably parallel, so that interstices are formed;
b) fortifying the interstices in the layer with osteoinductive compounds;
c) repeating steps a) and b) until a multilayer main structure is formed that at least partly embeds the connection element.

### Claim 17 (depends on 16)

The method according to claim 16, wherein the lines of the layer being deposited in step c) make an angle of 30 to 90 degrees, with the lines of the previous layer, so that a macroporous, interconnected structure is formed.

### Claim 18 (depends on 15)

The method according to claim 15, wherein a second main structure of biocompatible material comprising a cartilage substitute material or soft tissue substitute, is deposited at the same time or after the depositing of the main structure of bone substitute material.

### Claim 19 (depends on 1)

The biocompatible body according to claim 1, wherein the biocompatible body is a dental implant or an orthopedic implant.
