# US 2014/0193534 A1 · Epicatechin for alleviating symptoms of allergy

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- Number: US 2014/0193534 A1
- Document ID: US20140193534A1
- Status: Published application
- Kind: A1
- Application number: 14/240,134
- Filed: 2012-08-23
- Published: 2014-07-10
- Earliest claimed: 2011-08-24
- Assignees: Nestec S.A.
- Inventors: Annick Mercenier; Anurag Sigh; Sebastien Holvoet; Fabiola Dionisi; Lucas Actis Goretta
- Web page: https://patentgrep.com/patent/US20140193534A1

## CPC

- A61K 31/353: 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A23K 20/111: Aromatic compounds
- A23K 50/40: for carnivorous animals, e.g. cats or dogs
- A23L 33/105: Plant extracts, their artificial duplicates or their derivatives
- A61K 36/5777: {Theobroma, e.g. cocao or cocoa}
- A61K 36/73: Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K 36/82: Theaceae (Tea family), e.g. camellia
- A61P 1/00: Drugs for disorders of the alimentary tract or the digestive system
- A61P 1/08: for nausea, cinetosis or vertigo; Antiemetics
- A61P 1/12: Antidiarrhoeals
- A61P 11/02: Nasal agents, e.g. decongestants
- A61P 11/06: Antiasthmatics
- A61P 17/00: Drugs for dermatological disorders
- A61P 27/14: Decongestants or antiallergics
- A61P 37/08: Antiallergic agents (antiasthmatic agents A61P11/06; ophthalmic antiallergics A61P27/14)
- A61P 43/00: Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A23V 2002/00: Food compositions, function of food ingredients or processes for food or foodstuffs
- A23V 2200/00: Function of food ingredients
- A23V 2200/304: having a modulation effect on allergy and risk of allergy
- A23V 2200/318: having an effect on skin health and hair or coat
- A23V 2250/2116: Flavonoids, isoflavones
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A23K: FODDER
- A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A23V: INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION

## Abstract

The present invention relates to epicatechin for use in the prevention or reduction of symptoms of an allergic disorder and/or an allergic reaction. The invention further relates to epicatechin for said use in the form of food, food product, food supplement or pharmaceutical products.

## Claims

### Claim 1

A method for the secondary prevention of an allergic disorder and/or an allergic reaction in a patient in need of same comprising administering a composition comprising epicatechin.

### Claim 2 (depends on 1)

The method according to claim 1, wherein the allergic disorder is selected from the group consisting of skin allergy, allergic contact dermatitis, food allergy, allergic rhinitis and asthma.

### Claim 3 (depends on 1)

The method according to claim 1, wherein the secondary prevention is treating or preventing symptoms of an allergic disorder and/or an allergic reaction, wherein the symptoms are selected from the group consisting of gut discomfort, diarrhea, vomiting, skin irritation, atopic eczema, respiratory irritation, ocular irritation, and a combination thereof.

### Claim 4 (depends on 1)

The method according to claim 1, wherein the patient is a human being or a pet animal.

### Claim 5 (depends on 1)

The method according to claim 1, wherein the patient is selected from the group consisting of a young child between the age of 4 months and six years, an older child between the age of 6 to 18 years, and an adult person.

### Claim 6 (depends on 1)

The method according to claim 1, wherein the epicatechin is administered in an amount in the range from 25 mg to 10 g per day.

### Claim 7 (depends on 1)

The method according to claim 1, wherein the epicatechin is provided in the form of a plant extract or concentrate.

### Claim 8 (depends on 7)

The method according to claim 7, wherein the plant extract or concentrate is an extract or concentrate from a plant selected from the group consisting of apple, cocoa and tea.

### Claim 9 (depends on 1)

The method according to claim 1, wherein the epicatechin comprises at least 0.1 wt % of the composition.

### Claim 10 (depends on 1)

The method according to claim 1, wherein the epicatechin comprises at least 10 wt % of the composition.

### Claim 11 (depends on 1)

The method according to claim 1, wherein the composition is selected from the group consisting of a food product, a food supplement and a pharmaceutical product.

### Claim 12 (depends on 11)

The method according to claim 11, wherein the food product is selected from the group consisting of an infant feeding composition, a follow-up formula, a growing-up milk, an infant cereal, and a baby food product.

### Claim 13 (depends on 11)

The method according to claim 11, wherein the food product is selected from the group consisting of a beverage product, a yoghurt product, a fermented milk, a fruit juice, and a cereal bar.

### Claim 14 (depends on 11)

The method according to claim 11, wherein the food product is a food for specific medical purposes.

### Claim 15 (depends on 11)

The method according to claim 11, wherein the food product is a pet food product.