# US 2014/0193531 A1 · Aqueous extracts of deschampsia antarctica

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- Number: US 2014/0193531 A1
- Document ID: US20140193531A1
- Status: Published application
- Kind: A1
- Application number: 13/694,380
- Filed: 2012-11-27
- Published: 2014-07-10
- Earliest claimed: 2012-11-27
- Assignees: Uxmal S.A.
- Inventors: Gidekel Manuel
- Web page: https://patentgrep.com/patent/US20140193531A1

## CPC

- A61K 36/899: Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K 8/9794: Liliopsida [monocotyledons]
- A61K 9/19: lyophilised {, i.e. freeze-dried, solutions or dispersions (lyophilised products with subsequent particle size reduction A61K9/14; granules or pellets made by lyphilisation A61K9/1682; solid oral dosage forms made by lyophilisation A61K9/2095; lyophilisation additives A61K47/00)}
- A61Q 19/08: Anti-ageing preparations
- A61K 2236/00: Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K 2800/84: Products or compounds obtained by lyophilisation, freeze-drying
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

The present invention encompasses a method of preparing a pharmaceutically active extract of D. Antarctica comprising the steps of: a. Collecting and disinfecting D. Antarctica plants; b. Exposing the D. Antarctica plants to ultra pure water at a temperature of from 95° to 100° C. for a period of about 5 hours to yield a liquid extract of the plant; and c. Lyophilizing the liquid extract yielding a dry homogeneous product. In another embodiment, the present invention provides an anti-aging pharmaceutical composition useful in slowing down or reversing the aging process in human beings said composition comprising an aqueous extract of D. Antarctica. In a particular embodiment the aqueous extract comprises a polyphenolic free-radical scavenger present in the amount of at least 4.0% (w/w) and preferably at least 5.0% (w/w) In another embodiment the present invention provides a method of treatment for the prevention of photoaging effects generated by exposure to harmful ultraviolet radiation comprising the step of administering to a human being a therapeutically effective amount of the aqueous extract of D. Antarctica. Preferably the extract is administered in the form of a cream, paste or gel

## Claims

### Claim 1

A method of preparing a pharmaceutically active aqueous extract of D. Antarctica comprising the steps of:
a. Collecting and disinfecting D. Antarctica plants;
b. Exposing the D. Antarctica plants to ultra pure water at a temperature of from 95° to 100° C. for a period of about 5 hours to yield a liquid extract of the plant; and
c. Lyophilizing the liquid extract followed by separation of a dry homogeneous product.

### Claim 2 (depends on 1)

A pharmaceutical composition for slowing down or reversing the aging process in human beings comprising an aqueous extract of D. Antarctica according to claim 1.

### Claim 3 (depends on 2)

A pharmaceutical composition for slowing down or reversing the aging process according to claim 2 wherein said aqueous extract further comprises a polyphenolic free-radical scavenger.

### Claim 4 (depends on 1)

A pharmaceutical composition for the prevention of photoaging effects in human beings generated by exposure to harmful ultraviolet radiation comprising an aqueous extract of D. Antarctica according to claim 1.

### Claim 5 (depends on 1)

A method of treatment for slowing down or reversing the aging process in human beings comprising administering a therapeutically effective amount of an aqueous extract of D. Antarctica according to claim 1.

### Claim 6 (depends on 1)

A method of treatment for the prevention of photoaging effects in human beings generated by exposure to harmful ultraviolet radiation comprising administering a therapeutically effective amount of an aqueous extract of D. Antarctica according to claim 1.

### Claim 7 (depends on 3, 4)

A pharmaceutical composition according to claims 3 and 4 wherein said composition is in the form of a cream, paste or gel.

### Claim 8

An aqueous extract of D. Antarctica comprising a polyphenolic free-radical scavenger present in the amount of at least 4.0% (w/w).