Method for solubilising, dispersing and stabilising of substances, products manufactured according to the method as well as the use thereof
AssigneeBiorem AG
InventorHanspeter Strobel
Life of this patent
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AssigneeBiorem AG
InventorHanspeter Strobel
Estimating the term…
Disclosed is a method in which poloxamer, a resin, and/or a tocopherol is/are fused, and the material that is to be treated is intimately dispersed with said melt. After being introduced into the melt, the material that is to be treated is coated with water to prevent hardening, and the spontaneously forming gel is homogenized. The obtained product is composed of a transparent gel that is based on at least one poloxamer, a resin or a tocopherol, and an active substance which is solubilized, dispersed, and stabilized therein and whose consistency ranges from solid, semisolid, i.e. aspic-like, to liquid. The micelles of said solubilized matter remain stable even when the same is diluted well below the CMC of poloxamer.
A stabilized product comprising a transparent gel that comprises at least one polyoxyethylene-polyoxypropylene block copolymer (poloxamer), a natural or an artificially prepared resin and/or a tocopherol, and an active agent, said active agent being one or more substance selected from the group consisting of insulin, cyclosporine, polyphenyl compounds, propolis, selenium dioxide, tar, mineral oil, and plant extracts from holy thistle, passion flower and butterbur, including silymarin and chrysin;
Dependencies are inferred from the claim text.