# US 2014/0193455 A1 · Pharmaceutical composition for prevention or treatment of steroid-induced diabetes and health functional food

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- Number: US 2014/0193455 A1
- Document ID: US20140193455A1
- Status: Published application
- Kind: A1
- Application number: 13/737,148
- Filed: 2013-01-09
- Published: 2014-07-10
- Earliest claimed: 2013-01-09
- Inventors: Byoung Cheon KIM
- Web page: https://patentgrep.com/patent/US20140193455A1

## CPC

- A61K 36/07: Basidiomycota, e.g. Cryptococcus
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)

## Abstract

A pharmaceutical composition for preventing or treating steroid-induced diabetes (SID) and a health functional food, and more particularly to a pharmaceutical composition for preventing or treating SID and a health functional food, contain a Ceriporia lacerata culture extract as an active ingredient. The pharmaceutical composition and the health functional composition have the effect of protecting INS-1 insulin-secreting cells by blocking the steroid-mediated proliferation inhibition and apoptosis induction of INS-1 insulin-secreting cells. Thus, the pharmaceutical composition and the health functional composition can be developed as the active ingredient of pharmaceutical or functional food compositions serving to protect or regenerate β-cells by blocking the steroid-mediated growth inhibition and apoptosis of β-cells.

## Claims

### Claim 1

A pharmaceutical method for preventing or treating steroid-induced diabetes (SID), comprising a step for using a composition including a Ceriporia lacerata culture extract as an active ingredient.

### Claim 2

A pharmaceutical method for promoting survival of pancreatic β-cells, comprising a step for using a composition including a Ceriporia lacerata culture extract as an active ingredient.

### Claim 3

A pharmaceutical method for inhibiting apoptosis of pancreatic β-cells, comprising a step for using a composition including a Ceriporia lacerata culture extract as an active ingredient.

### Claim 4

A method for ameliorating steroid-induced diabetes (SID), comprising a step for using a health functional food including a Ceriporia lacerata culture extract as an active ingredient.