# US 2014/0193057 A1 · Methods and systems for transforming luminal images

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- Number: US 2014/0193057 A1
- Document ID: US20140193057A1
- Status: Published application
- Kind: A1
- Application number: 14/209,021
- Filed: 2014-03-13
- Published: 2014-07-10
- Earliest claimed: 2012-10-05
- Assignees: Volcano Corporation
- Applicants: Volcano Corporation
- Inventors: Vladimir Zagrodsky; Bernhard Sturm; Elizabeth Begin; Jason Sproul
- Web page: https://patentgrep.com/patent/US20140193057A1

## CPC

- G06T 7/33: using feature-based methods
- G06T 5/70: Denoising; Smoothing
- G06T 7/0012: {Biomedical image inspection}
- G06T 7/0014: {using an image reference approach}
- G06T 7/337: {involving reference images or patches}
- G06T 7/38: Registration of image sequences
- G06T 2207/10068: Endoscopic image
- G06T 2207/10101: Optical tomography; Optical coherence tomography [OCT]
- G06T 2207/10132: Ultrasound image
- G06T 2207/10136: 3D ultrasound image
- G06T 2207/30101: Blood vessel; Artery; Vein; Vascular
- G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL

## Abstract

The invention provides methods and systems for correcting translational distortion in a medical image of a lumen of a biological structure. The method facilitates vessel visualization in intravascular images (e.g. IVUS, OCT) used to evaluate the cardiovascular health of a patient. Using the methods and systems described herein it is simpler for a provider to evaluate vascular imaging data, which is typically distorted due to cardiac vessel-catheter motion while the image was acquired.

## Claims

### Claim 1

A system for transforming an image of a lumen, comprising:
a processor; and
storage coupled to the processor, the storage comprising instructions that when executed cause the processor to:
receive data corresponding to a first image of a lumen;
register coordinates of at least two points in the first image of the lumen;
receive data corresponding to a second image of a lumen;
register coordinates of at least two points in the second image of the lumen;
compare the coordinates of the at least two points in the first image of the lumen to the coordinates of the at least two points in the second image of the lumen;
determine a translation to align the at least two points in the first image of the lumen and the at least two points in the second image of the lumen; and
translate the first image or the second image of the lumen to align the at least two points in the first image of the lumen and the at least two points in the second image of the lumen.

### Claim 2 (depends on 1)

The system of claim 1, wherein the storage additionally comprises instructions to cause the processor to output data corresponding to an image comprising the first and second images of the lumen.

### Claim 3 (depends on 2)

The system of claim 2, wherein image comprising the first and second images is selected from a splayed image, an image longitudinal display (ILD) image, a three dimensional image, a tomographic image, or a combination thereof.

### Claim 4 (depends on 1)

The system of claim 1, wherein the lumen is a vessel.

### Claim 5 (depends on 1)

The system of claim 1, wherein the data corresponding to the images of the lumen is acquired with optical coherence tomography (OCT).

### Claim 6 (depends on 1)

The system of claim 1, wherein the data corresponding to the images of the lumen is acquired with intravenous ultrasound imaging (IVUS).

### Claim 7 (depends on 1)

The system of claim 1, wherein the translated image corrects for frame alignment distortion, device angular distortion, device translational distortion, helical offset distortion, cardiac motion distortions, or combination thereof.

### Claim 8 (depends on 7)

The system of claim 7, wherein the translated image corrects for frame alignment distortions.

### Claim 9 (depends on 1)

The system of claim 1, wherein the first and second images are taken consecutively in time.

### Claim 10 (depends on 1)

The system of claim 1, wherein the at least two points in the first image are points on a lumen border.

### Claim 11 (depends on 1)

The system of claim 1, wherein the storage additionally comprises instructions that cause the processor to smooth the data corresponding to an image comprising the first and second images of the lumen.

### Claim 12

A system for transforming an image of a lumen, comprising:
a processor; and
storage coupled to the processor, the storage comprising instructions that when executed cause the processor to:
receive data corresponding to a first image of a lumen;
register coordinates of at least two points in the first image of the lumen;
receive data corresponding to a second image of a lumen;
register coordinates of at least two points in the second image of the lumen;
receive data corresponding to a third image of a lumen;
register coordinates of at least two points in the third image of the lumen;
compare the coordinates of the at least two points in the first image of the lumen to the at least two points in the second image of the lumen and to the coordinates of the at least two points in the third image of the lumen;
determine a translation to align the at least two points in the first image of the lumen, the at least two points in the second image of the lumen, and the at least two points in the third image of the lumen; and
translate the first image to align the at least two points in the first image of the lumen, the at least two points in the second image of the lumen, and the at least two points in the third image of the lumen.

### Claim 13 (depends on 12)

The system of claim 12, wherein the storage additionally comprises instructions to cause the processor to output data corresponding to an image comprising the first, second, and third images of the lumen.

### Claim 14 (depends on 13)

The system of claim 13, wherein image comprising the first, second, and third images is selected from a splayed image, an image longitudinal display (ILD) image, a three dimensional image, a tomographic image, or a combination thereof.

### Claim 15 (depends on 12)

The system of claim 12, wherein the lumen is a vessel.

### Claim 16 (depends on 12)

The system of claim 12, wherein the third, first, and second images are taken consecutively in time.

### Claim 17 (depends on 12)

The system of claim 12, wherein the at least two points in the first image are points on a lumen border.

### Claim 18

A method comprising:
receiving data corresponding to a first image of a lumen;
registering coordinates of at least two points in the first image of the lumen;
receiving data corresponding to a second image of a lumen;
registering coordinates of at least two points in the second image of the lumen;
comparing the coordinates of the at least two points in the first image of the lumen to the coordinates of the at least two points in the second image of the lumen;
determining a translation to align the at least two points in the first image of the lumen and the at least two points in the second image of the lumen; and
translating the first image or the second image of the lumen to align the at least two points in the first image of the lumen and the at least two points in the second image of the lumen.

### Claim 19 (depends on 18)

The method of claim 18, further comprising outputting data corresponding to an image comprising the first and second images of the lumen.

### Claim 20 (depends on 19)

The method of claim 19, further comprising smoothing the data corresponding to an image comprising the first and second images of the lumen.
