# US 2014/0192532 A1 · Axial illumination for capillary electrophoresis

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- Number: US 2014/0192532 A1
- Document ID: US20140192532A1
- Status: Published application
- Kind: A1
- Application number: 14/107,651
- Filed: 2013-12-16
- Published: 2014-07-10
- Earliest claimed: 2005-02-16
- Assignees: Applied Biosystems, LLC
- Applicants: Applied Biosystems, LLC
- Inventors: Richard Reel; Eric Nordman
- Web page: https://patentgrep.com/patent/US20140192532A1

## CPC

- F21V 5/00: Refractors for light sources (characterised by cooling arrangements F21V29/504)
- G01N 21/64: Fluorescence; Phosphorescence
- G01N 21/645: {Specially adapted constructive features of fluorimeters}
- G01N 27/44721: {by optical means}
- G01N 2021/6463: {Optics}
- G01N 2201/068: Optics, miscellaneous
- Y10T 436/143333: Saccharide [e.g., DNA, etc.]
- F21V: FUNCTIONAL FEATURES OR DETAILS OF LIGHTING DEVICES OR SYSTEMS THEREOF; STRUCTURAL COMBINATIONS OF LIGHTING DEVICES WITH OTHER ARTICLES, NOT OTHERWISE PROVIDED FOR
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)
- Y10T: TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION

## Abstract

System and method for fluorescent light excitation and detection from samples to enhance the numerical aperture and/or reduce the cross-talk of the fluorescent light.

## Claims

### Claim 1

An excitation system for analyzing samples comprising:
a non-coherent light source;
a housing, wherein the housing transports samples and propagates light from the non-coherent light source by total internal reflection; and
a coupling optical element configured to introduce light from the non-coherent light source into the housing through a wall of the housing.

### Claim at position 2

2-37. (canceled)