# US 2014/0192324 A1 · Spectral domain optical coherence tomography system

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- Number: US 2014/0192324 A1
- Document ID: US20140192324A1
- Status: Published application
- Kind: A1
- Application number: 14/155,148
- Filed: 2014-01-14
- Published: 2014-07-10
- Earliest claimed: 2006-06-20
- Assignees: Carl Zeiss Meditec AG
- Applicants: Carl Zeiss Meditec, Inc.
- Inventors: Jochen STRAUB; Clement Louis-Rene VIARD
- Web page: https://patentgrep.com/patent/US20140192324A1

## CPC

- G01B 9/02077: {of the object}
- A61B 3/102: {for optical coherence tomography [OCT]}
- G01B 9/0203: {With imaging systems}
- G01B 9/02044: {Imaging in the frequency domain, e.g. by using a spectrometer}
- G01B 9/02091: Tomographic interferometers, e.g. based on optical coherence
- G01N 21/4795: {spatially resolved investigating of object in scattering medium (in vivo A61B)}
- G01B 2290/65: Spatial scanning object beam
- G01B 2290/70: Using polarization in the interferometer
- G01B: MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)

## Abstract

An optical coherence tomography device is disclosed for improved imaging. Reduced levels of speckle in the images generated by the device are obtained by forming a B-scan from a plurality of A-scans, wherein each resolution cell of the B-scan is generated through compounding of a subset of the A-scans and wherein at least some of the subset of A-scans are separated by at least half the diameter of a speckle cell both tangent to and orthogonal to the B-scan at that cell.

## Claims

### Claim 1

(canceled)

### Claim 2

A retinal imaging device comprising:
a first imaging system having a detection component conjugate to an image plane in a first structure of the retina;
a second imaging system having a detection component conjugate to an image plane in a second structure of the retina;
wherein the first and second structures of the retina are located at different depths within the retina; and
wherein the first and second imaging systems share a common portion of an optical path.

### Claim 3 (depends on 2)

A retinal imaging device as recited in claim 2, wherein the first imaging system is an optical coherence tomography (OCT) system and the second imaging system is a fundus imaging system.

### Claim 4 (depends on 3)

A retinal imaging device as recited in claim 3, wherein the OCT system is conjugate to the retinal pigment epithelium (RPE) layer and the fundus imaging system is conjugate to choroidal vessels.

### Claim 5 (depends on 3)

A retinal imaging device as recited in claim 3, wherein the OCT system is conjugate to a layer anterior to the RPE layer and the fundus imaging system is conjugate to choroidal vessels.

### Claim 6 (depends on 3)

A retinal imaging device as recited in claim 3, wherein the fundus imaging system is conjugate to a to a structure located anterior to the conjugate of the OCT system.

### Claim 7 (depends on 3)

A retinal imaging device as recited in claim 3, wherein the first structure is blood vessels and the second structure is a retinal layer.

### Claim 8 (depends on 2)

A retinal imaging device as recited in claim 2, wherein the first imaging system is a retinal imager and the associated image plane corresponds to a layer posterior to the RPE and the second imaging system is a scanning retinal imager and the associated image plane is located anterior to the image plane of the first imaging system.

### Claim 9 (depends on 2)

A retinal imaging device as recited in claim 2, further comprising an iris viewing system.

### Claim 10 (depends on 2)

A retinal imaging device as recited in claim 2, wherein the first imaging system is configured to receive visible light and the second imaging system is configured to receive near-infrared light.

### Claim 11 (depends on 2)

A retinal imaging device as recited in claim 2, wherein the first imaging system is an OCT scanner and the second imaging system is a scanning fundus imaging system.

### Claim 12 (depends on 11)

A retinal imaging device as recited in claim 11, wherein the scanning fundus imaging system is one of a scanning laser ophthalmoscope, a line scanning laser ophthalmoscope, or a line scanning ophthalmoscope.

### Claim 13 (depends on 11)

A retinal imaging device as recited in claim 11, wherein the scanning fundus imaging system is conjugate to a structure located anterior to the conjugate of the OCT system.

### Claim 14 (depends on 2)

A retinal imaging device as recited in claim 2 wherein said first structure is one layer of the retina and the second structure is a different layer of the retina.