# US 2014/0190846 A1 · Medical device comprising a wetted hydrophilic coating > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2014/0190846 A1 - Document ID: US20140190846A1 - Status: Published application - Kind: A1 - Application number: 14/115,920 - Filed: 2012-07-27 - Published: 2014-07-10 - Earliest claimed: 2011-07-29 - Assignees: Dsm IP Assets B.V. - Inventors: Johannes Wilhelmus Belt - Web page: https://patentgrep.com/patent/US20140190846A1 ## CPC - B65D 81/24: Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants (with thermal insulation B65D81/38) - A61L 29/085: {Macromolecular materials} - A61L 29/14: Materials characterised by their function or physical properties {, e.g. lubricating compositions} - B65B 5/04: Packaging single articles - A61L 2400/10: Materials for lubricating medical devices - B65D: CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) - B65B: MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING (bundling and pressing devices for cigars A24C1/44; devices for tensioning and securing binders adapted to be supported by the article or articles to be bound B25B25/00; applying closure members to bottles, jars or similar containers B67B1/00-B67B6/00; concurrent cleaning, filling and closing of bottles B67C7/00; emptying bottles, jars, cans, casks, barrels or similar containers B67C9/00) ## Abstract The invention is directed to the use of a wetting agent having a boiling point higher than 100° C. and a viscosity lower than 500 mPa.s, wherein the wetting agent comprises water in an amount between 0 and 4.9 wt % based on the total weight of the wetting agent, for the lubrication of a hydrophilic polymer coating. The invention further relates to a medical device comprising a hydrophilic polymer coating that is wetted by a wetting agent, a method for the preparation of a medical device and a package comprising a medical device. ## Claims ### Claim at position 1 -13. (canceled) ### Claim 14 A package comprising a medical device, the medical device comprising: a hydrophilic polymer coating that is wetted by a wetting agent having a boiling point higher than 100° C. and a viscosity lower than 500 mPa.s, wherein the wetting agent comprises water in an amount between 0 and 4.9 wt % based on the total weight of the wetting agent, wherein the package is impermeable to vapor, and wherein the medical device is sterilized. ### Claim 15 (depends on 14) The package according to claim 14, wherein the wetting agent comprises at least one hydroxyl group. ### Claim 16 (depends on 14) The package according to claim 14, wherein the wetting agent is chosen from the group consisting of glycerol esters, glycerol ethers, glycols, glycolesters and glycolethers. ### Claim 17 (depends on 14) The package according to claim 14, wherein the hydrophilic polymer coating is crosslinked. ### Claim 18 (depends on 14) The package according to claim 14, wherein the hydrophilic polymer coating comprises polyvinylpyrrollidone (PVP). ### Claim 19 (depends on 14) The package according to claim 14, wherein the dry-out time of the hydrophilic polymer coating is longer than 15 minutes as determined on a Harland Friction tester. ### Claim 20 (depends on 14) The package according to claim 14, wherein the hydrophilic polymer coating has a coefficient of friction lower than 0.2 as determined on a Harland Friction tester. ### Claim 21 (depends on 14) The package according to claim 14, wherein the medical device is sterilized by applying electron beam, x-ray or gamma ray irradiation. ### Claim 22 (depends on 14) The package according to claim 14, wherein the wetting agent comprises a member of the group consisting of glycerol, monoacetin, diacetin and diacetone alcohol. ### Claim 23 (depends on 14) The package according to claim 14, wherein the wetting agent comprises propyleneglycol. ### Claim 24 (depends on 14) The package according to claim 14, wherein the wetting agent consists of propyleneglycol. ### Claim 25 (depends on 14) The package according to claim 14, wherein the wetting agent further comprises a stabilizing compound. ### Claim 26 (depends on 14) The package according to claim 14, wherein the wetting agent comprises an alkylene alcohol. ### Claim 27 (depends on 14) The package according to claim 14, wherein the wetting agent comprises a member of the group consisting of diethyleneglycol, triethyleneglycol, tetraethyleneglycol, propyleneglycol, dipropyleneglycol, triprolyeneglycol, ethanolamine, diethanolamine, triethanolamine, and polyethylene glycol. ### Claim 28 (depends on 14) The package according to claim 14, wherein the wetting agent comprises a polyalkylene glycol. ### Claim 29 (depends on 23) The package according to claim 23, wherein the medical device is sterilized by applying electron beam, x-ray or gamma ray irradiation. ### Claim 30 (depends on 24) The package according to claim 24, wherein the medical device is sterilized by applying electron beam, x-ray or gamma ray irradiation. ### Claim 31 (depends on 27) The package according to claim 27, wherein the medical device is sterilized by applying electron beam, x-ray or gamma ray irradiation. ### Claim 32 (depends on 28) The package according to claim 28, wherein the medical device is sterilized by applying electron beam, x-ray or gamma ray irradiation. ### Claim 33 A method for the preparation of a medical device comprising the steps of: (a) providing a medical device that is at least partially coated with a hydrophilic polymer coating, (b) providing a wetting agent with a boiling point higher than 100° C. and a viscosity lower than 500 mPa.s, wherein the wetting agent comprises water in an amount between 0 and 4.9 wt % based on the total weight of the wetting agent, (c) contacting the part of the medical device that is coated with the hydrophilic polymer coating with the wetting agent in such a way that the hydrophilic coating is lubricated by the wetting agent, and (d) sterilizing the medical device.