Methods and apparatus for analyzing genetic information
AssigneeSamsung Electronics Co., Ltd.
InventorsEun-jin LEE, Tae-jin AHN
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Abstract
Provided are a method and apparatus for analyzing genetic information to acquire expression data of a subject with respect to gene expression patterns of genes included in a gene network and determine a genetic abnormality of the gene network included in the expression data of the subject by using a representative expression pattern estimated from a group of normal people.
Claims20
A computer-implemented method of analyzing genetic information, the method comprising the steps, implemented in a processor, of:
- receiving first expression data of a group of normal people and second expression data of a subject with respect to gene expression patterns of genes included in a gene network;
- calculating an estimate of a representative expression pattern summarizing a distribution of the gene expression patterns of individuals belonging to the group of normal people, which are included in the first expression data;
- analyzing a distribution of a similarity of each of the estimated gene expression patterns of the individuals and the subject with respect to the representative expression pattern;
- and
- determining a genetic abnormality of the gene network of the subject, which is included in the acquired second expression data, based on the analyzed distribution of the similarity.
A non-transitory computer-readable storage medium having stored therein program instructions, which when executed by a processor, cause the processor to:
- receive first expression data of a group of normal people and second expression data of a subject with respect to gene expression patterns of genes included in a gene network;
- calculate an estimate of a representative expression pattern summarizing a distribution of the gene expression patterns of individuals belonging to the group of normal people, which are included in the acquired first expression data;
- analyze a distribution of a similarity of each of the estimated gene expression patterns of the individuals and the subject with respect to the representative expression pattern;
- and
- determine a genetic abnormality of the gene network of the subject, which is included in the second expression data, based on the analyzed distribution of the similarity.
An apparatus for analyzing genetic information, the apparatus comprising:
- a unit that receives or acquires first expression data of a group of normal people and second expression data of a subject with respect to gene expression patterns of genes included in a gene network;
- an estimating unit that calculates an estimate of a representative expression pattern summarizing a distribution of the gene expression patterns of individuals belonging to the group of normal people, which are included in the first expression data;
- an analyzing unit that analyzes a distribution of a similarity of each of the gene expression patterns of the individuals and the subject with respect to the representative expression pattern;
- and
- a determining unit that determines a genetic abnormality of the gene network of the subject, which is included in the acquired second expression data, based on the analyzed distribution of the similarity.
Dependencies are inferred from the claim text.