Dynamic bioactive nanofiber scaffolding
AssigneeMo-Sci Corporation
InventorsThomas E. Day, Erik M. Erbe, Steven B. Jung
Life of this patent
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Abstract
A resorbable bone graft scaffold material, including a plurality of overlapping and interlocking fibers defining a scaffold structure, plurality of pores distributed throughout the scaffold, and a plurality of glass microspheres distributed throughout the pores. The fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and the fibers are a bioactive, resorbable material. The fibers generally contribute about 20 to about 40 weight percent of the scaffold material, with the microspheres contributing the balance.
Claims19
A resorbable bone graft scaffold material, comprising:
- a plurality of overlapping and interlinking nonporous, polymer-free bioactive ceramic fibers defining a scaffold structure;
- a plurality of pores distributed throughout and defined by the scaffold;
- and
- a plurality of bioactive, resorbable spheres distributed in at least some of the respective pores;
- wherein each respective sphere is fused to at least one ceramic fiber;
- wherein the fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers;
- wherein the fibers are a bioactive, resorbable material.
12-21. (canceled)
A biologically resorbable tissue regrowth scaffold material, comprising:
- a porous support matrix further defining a plurality of overlapping and entangled solid, polymer-free bioactive, resorbable ceramic fibers;
- a plurality of pores distributed throughout the support matrix;
- and
- a plurality of bioactive, resorbable spheres distributed throughout the support matrix;
- wherein each respective fiber has a diameter from about 5 nanometers to about 100 micrometers.
A tissue regrowth support material, comprising:
- a flexible porous fibrous tissue regrowth support material further comprising a plurality of overlapping and entangled bioactive, biologically resorbable ceramic fibers;
- a plurality of pores distributed throughout the support material;
- and
- a plurality of bioactive, resorbable particles distributed throughout the support matrix.
Dependencies are inferred from the claim text.