Bioabsorbable Medical Devices and Methods of Use Thereof
AssigneeCook Medical Technologies LLC
InventorsKeith R. Milner, James M. Carlson, Steven Charlebois, Krista N. Gearhart, Richard A. Swift
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Abstract
One aspect provides implantable medical devices including a bioabsorbable structure having a surface and having a coating layer on at least a portion of the surface. In certain embodiments, the coating layer includes a releasable bioactive and provides for a controlled absorption of the bioabsorbable structure upon implantation in a human or veterinary patient. Another aspect provides methods treating a disease including implanting such a device in a vessel of a human or veterinary patient.
Claims20
An implantable medical device comprising:
- a structure having a surface and comprising a bioabsorbable base material;
- and
- a coating layer on at least a portion of the surface,
- wherein the coating layer provides for a controlled absorption of the base material.
A method of locally delivering a bioactive agent within a body vessel, comprising
- inserting an expandable medical device into the vascular system of a patient, the device comprising (i) a structure having a surface and comprising a bioabsorbable base material, and (ii) a coating layer on at least a portion of the surface, wherein the coating layer provides for a controlled absorption of the base material,
- radially expanding the medical device within the body vessel to bring a vessel wall in contact with the device, and
- maintaining the expanded device in contact with the vessel wall for a time sufficient to deliver a therapeutically effective amount of the bioactive agent to the vessel wall.
An implantable stent comprising:
- a structure having a surface and comprising a bioabsorbable metal;
- and
- a coating layer encapsulating the surface,
- wherein the coating layer comprises dihydrate paclitaxel and provides for a controlled absorption of the base material.
Dependencies are inferred from the claim text.