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US 2014/0179979 A1Published application
Therapeutic agent applicators and methods of using the same
AssigneesH. Lee Moffitt Cancer Center and Research Institute, Inc., University of South Florida
InventorsSteven E. Finkelstein, Matthew C. Biagioli, Mayer N. Fishman
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Abstract
The present application relates to applicators and methods for administering therapeutic agents to cancerous tissue. The applicators can be used to deliver radiation and additional therapeutic agents to cancerous tissue located in a subject.
Claims36
A device for administration of at least one therapeutic agent to cancerous tissue, comprising:
- an applicator with an elongate portion and having a distal end, said elongate portion defining a lumen configured to direct passage of the therapeutic agent towards the distal end, wherein the applicator further comprises at least one opening spaced from the distal end and in communication with the lumen, the opening configured for directing the therapeutic agent from the lumen to the cancerous tissue.
A method for treating cancerous tissue comprising:
- positioning an applicator in, or in proximity to, the cancerous tissue, wherein the applicator comprises a lumen configured to house a radiation source;
- advancing the radiation source through the applicator to a position where it irradiates at least a portion of the cancerous tissue;
- removing the radiation source from its irradiating position;
- and
- administering a therapeutic agent to the irradiated cancerous tissue, wherein the administration is performed directly to the irradiated cancer tissue.
2 more elements
Dependencies are inferred from the claim text.