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US 2014/0179796 A1Published application
Markers for dcis recurrence: coordinate pten/rb loss
AssigneeThomas Jefferson University
InventorsAgnieszka WITKIEWICZ, Erik KNUDSEN, Gordon SCHWARTZ
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Abstract
The technology described herein relates to compositions, kits, assays, systems and methods relating to breast cancer and the treatment thereof.
Claims23
(canceled)
A method of administering a treatment for ductal carcinoma in situ (DCIS) to a subject, the method comprising:
- subjecting a test sample of a subject to at least one analysis to determine the level of expression of both (a) retinoblastoma 1 (RB) and (b) phosphatase and tensin homolog (PTEN);
- and
- administering a treatment for DCIS to the subject if the expression level of both RB and PTEN is decreased relative to a reference level;
- wherein the treatment is not a lumpectomy.
1 more element
Dependencies are inferred from the claim text.