Cocrystals of (n,n-diethylcarbamoyl)methyl methyl (2e)but-2-ene-1,4-dioate
AssigneeXenoPort, Inc.
InventorsChen Mao, Scott L. Childs
Life of this patent
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Abstract
Disclosed herein are cocrystals of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, which is a prodrug of methyl hydrogen fumarate.
Claims63
A cocrystal of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate and urea.
A cocrystal of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate and fumaric acid.
A cocrystal of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate and succinic acid.
A cocrystal of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate and maleic acid.
A cocrystal of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate and malic acid.
A cocrystal of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate and citric acid.
49 A pharmaceutical composition comprising a cocrystal according to claim 1 and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.