Nucleic acids involved in viral infection
AssigneeRosetta Genomics Ltd.
InventorsIssac Bentwich, Amir Avniel, Ranit Aharonov, Yael Karov, Yonat Shemer-Avni, Asaf Levy
Life of this patent
Estimating the term…
Abstract
Provided herein are isolated viral and human nucleic acids associated with viral infection and various nucleic acid molecules relating thereto or derived therefrom. The nucleic acids may be useful for the prevention, treatment and diagnosis of viral infections.
Claims12
-6. (canceled)
A method of preventing or treating viral infection or a condition associated with a viral infection in a subject in need thereof comprising administering to the subject an effective amount of a composition comprising a nucleic acid sequence selected from the group consisting of SEQ ID NOS:
- 1-9,221, 15,366-15,392 and 15,516-15,527;
- a complementary sequence thereof;
- and a sequence at least about 80% identical thereto.
A method of inhibiting expression of a target gene in a cell comprising introducing a nucleic acid into the cell in an amount sufficient to inhibit expression of the target gene, wherein the target gene comprises a binding site substantially identical to a binding site as set forth in any one of SEQ ID NOS:
- 9,222-15,365, 15,393-15,515;
- and wherein the nucleic acid is a nucleic acid selected from the group consisting of SEQ ID NOS:
- 1-9,221, 15,366-15,392, and 15,516-15,527;
- a complementary sequence thereof;
- and a sequence at least about 80% identical thereto.
-18. (canceled)
A method of reducing the amount of virus replication in a target cell, said method comprising:
- introducing into a target cell infected with the virus an effective amount of a composition comprising a nucleic acid sequence selected from the group consisting of SEQ ID NOS:
- 1-9,221, 15,366-15,392 and 15,516-15,527;
- a complementary sequence thereof;
- and a sequence at least about 80% identical thereto.
Dependencies are inferred from the claim text.