Local cochlear application of statins for stimulating neurite regrowth in the cochlea
AssigneeNorthwestern University
InventorsDonna S. Whitlon, Claus-Peter Richter
Life of this patent
Estimating the term…
Abstract
Statin compositions are disclosed for stimulating neurite growth from spiral ganglion neurons in the inner ear and methods for preventing damage to or treating damage of auditory neurons and/or hair cells of the cochlea following acoustic or toxic insult.
Claims20
A pharmaceutical composition for preventing or treating hearing loss in a subject, comprising a statin or a pharmaceutically acceptable salt thereof.
A method of stimulating neurite growth from spiral ganglion neurons in the inner car, comprising contacting a neurite with a statin, or a pharmaceutically acceptable salt thereof.
A method of preventing or treating hearing loss in a subject, comprising administering to the subject a statin or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.