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US 2014/0179690 A1Published application
Fused aminodihydrothiazine derivatives
AssigneeEisai R&D Management Co., Ltd.
InventorsMamoru Takaishi, Tasuku Ishida
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Abstract
The present invention relates to a fused aminodihydrothiazine derivative of formula (I): wherein X is hydrogen or fluorine; R is monofluoromethyl or difluoromethyl; and pharmaceutically acceptable salts thereof; which compound has an Aβ production inhibitory effect or a BACE1 inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by Aβ and typified by Alzheimer-type dementia.
Claims16
A compound of formula (I):
- or a pharmaceutically acceptable salt thereof,
- wherein
- X is hydrogen or fluorine;
- R is monofluoromethyl or difluoromethyl.
1 more element
(canceled)
(canceled)
(canceled)
Dependencies are inferred from the claim text.